Tetracycline hydrochloride

Basic Information

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CAS Number

64-75-5

Molecular Formula

C22H24N2O8.HCl

Molecular Weight

480.9 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

214°C(dec.)

Boiling Point

799.4 °C at 760 mmHg

Density

1.1770

Water Solubility

50 g/L

Flash Point

437.3 °C

Solubility

H2O: 10 mg/mL as a stock solution. Stock solutions should be filtered sterilized and stored at −20°C. Stable at 37°C for 4 days.

Refractive Index

-253 ° (C=0.5, 0.1mol/L HCl)

Specific Rotation

-252 º (c=0.5, H2O)

SMILES

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CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl

InChI

InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1

InChIKey

YCIHPQHVWDULOY-FMZCEJRJSA-N

LogP

0.0508000000000004

Topological Polar Surface Area

181.62000000000003 Å²

Hydrogen Bond Donor/Acceptor

7 / 10

Complexity

971

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 3 Class 3

Stability

Stable. Incompatible with strong oxidizing agents.

Sensitiveness

Air & Light Sensitive

Toxicity

LD50 orally in rats: 6443 mg/kg (Goldenthal)

Synonyms & References

English

(-)-Tetrahcycline hydrochloride
TETRACYCLINE HYDROCHLORIDE [WHO-DD]
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aS,6S,12aS)-
AKOS015951263
DTXCID701321
NCI-C55561
P6R62377KV
PharmaVetResiMix 5 Tetracyclines-v10 10 microg/mL in Methanol
SR-01000000212
SR-05000001723
CHEMBL454950
TETRACYCLINE HYDROCHLORIDE [VANDF]
Tetracycline hydrochloride, European Pharmacopoeia (EP) Reference Standard
CCRIS 2351
Tetracaps
Achromycin hydrochloride
Tetracycline hydrochloride (internal use)
Telotrex
Tetracycline hydrochloride (JP17/USP)
(4S,4aS,5aS,6S,12aS,Z)-2-(amino(hydroxy)methylene)-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
SR-01000000212-4
Tetracycline hydrochloride 100 microg/mL in Acetonitrile
(4S,4AS,5aS,6S,12aS)-4-(Dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide hydrochloride
NSC-757338
TETRACYCLINE HYDROCHLORIDE [EP MONOGRAPH]
Tetrakap
Tetraciclina cloridrato [Italian]
2-naftacencarboxamida, 4-(dimetilamino)-1,4,4a, 5,5a, 6,11,12 a-octahidro-3, 6,10,12,12a-pentahidroxi-6-metil-1,11-dioxo-, clorhidrato (1:1), (4s, 4as, 5as, 6s, 12as)-
HMS1921C19
CCG-39267
Tet-cy

MDL Number

MFCD26794217

Customs Code

29413000

FAQ

What is Tetracycline hydrochloride (CAS: 64-75-5)?

Tetracycline hydrochloride is an antibiotic compound with the chemical formula C22H24N2O10Cl2. It is a salt form of tetracycline, commonly used in pharmaceutical applications for its broad-spectrum antibacterial activity. This compound is known for its stability and solubility in water, making it suitable for various formulations.

What are the main uses of Tetracycline hydrochloride (CAS: 64-75-5)?

Tetracycline hydrochloride is primarily used as an antibiotic to treat bacterial infections, including respiratory, urinary, and skin infections. It is also utilized in veterinary medicine, food preservatives, and research for antimicrobial studies. Due to its broad-spectrum activity, it is a key compound in pharmaceutical manufacturing.

Is Tetracycline hydrochloride (CAS: 64-75-5) safe?

Tetracycline hydrochloride is generally safe when used as directed, but it may cause side effects such as gastrointestinal discomfort or photosensitivity. It is important to follow proper handling precautions and safety guidelines to minimize risks. The compound is regulated under safety standards to ensure its appropriate use in medical and industrial contexts.

How should Tetracycline hydrochloride (CAS: 64-75-5) be stored?

Tetracycline hydrochloride should be stored in a cool, dry place away from direct light. It is typically kept at a temperature between 15°C to 25°C and in a sealed container to maintain its stability and potency. Proper storage conditions are essential to prevent degradation and ensure effectiveness.