5-Oxo-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-asparagine | CAS No. 63958-90-7

5-Oxo-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-asparagine

Basic Information

CAS Number

63958-90-7

Molecular Formula

C33H54N12O15

Molecular Weight

858.86 g/mol

AD

Basic Physical Properties

Density

1.417±0.06 g/cm3 (20 ºC 760 Torr),

CC(C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NCC(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)O)NC(=O)C1CCC(=O)N1

InChI

InChI=1S/C33H54N12O15/c1-15(39-29(55)18-6-8-24(50)40-18)27(53)42-16(4-2-3-9-34)30(56)45-21(14-47)32(58)43-17(5-7-22(35)48)28(54)38-11-25(51)37-12-26(52)41-20(13-46)31(57)44-19(33(59)60)10-23(36)49/h15-21,46-47H,2-14,34H2,1H3,(H2,35,48)(H2,36,49)(H,37,51)(H,38,54)(H,39,55)(H,40,50)(H,41,52)(H,42,53)(H,43,58)(H,44,57)(H,45,56)(H,59,60)/t15-,16-,17-,18-,19-,20-,21-/m0/s1

InChIKey

LIFNDDBLJFPEAN-BPSSIEEOSA-N

LogP

-9.234800000000014

Topological Polar Surface Area

451.8599999999999 Ų

Hydrogen Bond Donor/Acceptor

18 / 27

Complexity

1610

Synonyms & References

English

  • nonathymuline
  • Thymic factor
  • Thymalin
  • (3S,6S,9S,12S,21S,24S)-24-(2-amino-2-oxoethyl)-12-(3-amino-3-oxopropyl)-6-(4-aminobutyl)-9,21-bis(hydroxymethyl)-3-methyl-1,4,7,10,13,16,19,22-octaoxo-1-((S)-5-oxopyrrolidin-2-yl)-2,5,8,11,14,17,20,23-octaazapentacosan-25-oic acid
  • Thymulin (pig peptide moiety)
  • (2S)-4-amino-2-[[(2S)-2-[[2-[[2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-4-oxobutanoic acid
  • DTXCID00136292
  • SMR000058784
  • Thymulin
  • SCHEMBL2109423
  • MLS000028679
  • UNII-9H198D04WL
  • CS-0169099
  • (sup 2)N-(N-(N-(N-(sup 2)N-(N-(sup 2)N-(N-(-5-Oxo-L-prolyl)-L-alanyl)-L-seryl)-L-glutaminyl)glycyl)glycyl)-L-seryl)-L-asparagine.
  • DTXSID10213801
  • nonathymulinum
  • pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH
  • ((S)-5-Oxopyrrolidine-2-carbonyl)-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-asparagine
  • Thymulin Acetate
  • HY-P3206
  • MFCD00076882
  • GLXC-25916
  • N(sup 2)-(N-(N-(N-(N(sup 2)-(N-(N(sup 2)-(N-(-5-Oxo-L-prolyl)-L-alanyl)-L-lysyl)-L-seryl)-L-glutaminyl)glycyl)glycyl)-L-seryl)-L-asparagine
  • Q2007601
  • Thymulin, lyophilized powder
  • Nonathymulin [INN]
  • NS00123149
  • CHEMBL2106455
  • Thymuline
  • 9H198D04WL
  • L-ASPARAGINE, 5-OXO-L-PROLYL-L-ALANYL-L-LYSYL-L-SERYL-L-GLUTAMINYLGLYCYLGLYCYL-L-SERYL-

MDL Number

MFCD00076882

FAQ

What regulatory guidelines apply to 5-Oxo-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-asparagine (CAS: 63958-90-7)?

The compound 5-Oxo-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-asparagine (CAS: 63958-90-7) is subject to various regulatory guidelines. Under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), it is classified based on its physical and chemical properties. In the European Union, it must comply with the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation. Additionally, the U.S. Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) have specific requirements for the handling and use of this compound in pharmaceutical and industrial applications.

Are there alternatives to 5-Oxo-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-asparagine (CAS: 63958-90-7) in synthesis?

There are several alternatives to 5-Oxo-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-asparagine (CAS: 63958-90-7) in synthesis. These include amino acid analogs such as 5-Oxo-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-aspartic acid, and isomers like 5-Oxo-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-asparaginylglycine. Common alternative reagents include various coupling agents and chiral catalysts that can facilitate the synthesis of similar peptides or analogs.

What is the market or research trend for 5-Oxo-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-asparagine (CAS: 63958-90-7)?

The market for 5-Oxo-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-asparagine (CAS: 63958-90-7) is driven by its applications in pharmaceutical research, particularly in the development of peptide-based drugs. Recent research trends focus on the optimization of synthesis methods and the exploration of its potential in therapeutic areas such as inflammation and pain management. The demand is also influenced by the growing interest in biotechnology and personalized medicine.

How should waste containing 5-Oxo-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-asparagine (CAS: 63958-90-7) be handled?

Waste containing 5-Oxo-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-asparagine (CAS: 63958-90-7) should be managed according to regulatory guidelines. Proper waste collection and disposal methods include the use of appropriate containers to prevent contamination. For liquid waste, it should be collected in sealed, labeled containers and disposed of through a licensed waste management facility. Incineration is another disposal method, but it must be performed in a controlled and environmentally safe manner to minimize the release of harmful substances into the environment.

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