Olanzapine Impurity 17

Basic Information

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CAS Number

639460-79-0

Molecular Formula

C17H18N4OS

Molecular Weight

326.42 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Yellow to Brown

Boiling Point

563.4±60.0 °C(Predicted)

Density

1.39±0.1 g/cm3(Predicted)

Solubility

Chloroform, Methanol (Sparingly)

SMILES

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S1C(C)=CC2=C1NC1C=CC=CC=1N=C2N1CCN(C=O)CC1

InChI

1S/C17H18N4OS/c1-12-10-13-16(21-8-6-20(11-22)7-9-21)18-14-4-2-3-5-15(14)19-17(13)23-12/h2-5,10-11,19H,6-9H2,1H3

InChIKey

SFWJCBPXQCTXTO-UHFFFAOYSA-N

LogP

2.9658200000000017

pKa

7.78±0.20(Predicted)

Topological Polar Surface Area

47.940000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

477

Synonyms & References

English

SFWJCBPXQCTXTO-UHFFFAOYSA-N
Olanzapine N-ForMyl IMpurity
N-DeMethyl-N-forMylolanzapine
N-formyl Olanzapine
Olanzapine N-monoacyl impurities
1-Piperazinecarboxaldehyde, 4-(2-methyl-10H-thieno[2,3-b][1,5]benzodiazepin-4-yl)-
N-Demethyl-N-formylolanzapine
OLANZAPINE IMPURITY 5
CID 135503649
4-(2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-yl)piperazine-1-carbaldehyde

FAQ

What is Olanzapine Impurity 17 (CAS: 639460-79-0)?

Olanzapine Impurity 17 (CAS: 639460-79-0) is a by-product of the synthesis of olanzapine, an atypical antipsychotic medication used to treat schizophrenia and bipolar disorder. It is characterized by its chemical structure and properties similar to olanzapine but with variations that affect its pharmacological activity.

What are the main uses of Olanzapine Impurity 17 (CAS: 639460-79-0)?

Olanzapine Impurity 17 (CAS: 639460-79-0) is primarily used in the pharmaceutical industry as a reference standard for quality control and impurity analysis during the manufacture of olanzapine. It plays a critical role in ensuring the purity and efficacy of olanzapine medications.

Is Olanzapine Impurity 17 (CAS: 639460-79-0) safe?

Olanzapine Impurity 17 (CAS: 639460-79-0) is generally safe when handled under proper laboratory conditions. However, it is important to follow all safety guidelines, including wearing appropriate personal protective equipment (PPE) and ensuring proper ventilation. Exposure to this impurity can be harmful if ingested or inhaled, and it should be disposed of according to hazardous waste regulations.

How should Olanzapine Impurity 17 (CAS: 639460-79-0) be stored?

Olanzapine Impurity 17 (CAS: 639460-79-0) should be stored in a cool, dry place, away from direct sunlight and high temperatures. It should be kept in a tightly sealed container to prevent contamination and degradation. Optimal storage conditions include a temperature range of 15-25°C (59-77°F) and a relative humidity below 60%. Proper containerization is essential to maintain the stability and safety of the impurity during storage and transportation.