N-(3-Amino-4-methoxyphenyl)acetamide

Basic Information

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CAS Number

6375-47-9

Molecular Formula

C9H12N2O2

Molecular Weight

180.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

109°C

Boiling Point

313.03°C (rough estimate)

Density

1.1819 (rough estimate)

Flash Point

321°C

Refractive Index

1.5373 (estimate)

SMILES

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CC(=O)NC1=CC(=C(C=C1)OC)N

InChI

InChI=1S/C9H12N2O2/c1-6(12)11-7-3-4-9(13-2)8(10)5-7/h3-5H,10H2,1-2H3,(H,11,12)

InChIKey

SJWQCBCAGCEWCV-UHFFFAOYSA-N

LogP

1.2357999999999998

Topological Polar Surface Area

64.35 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

185

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

CHEMBL3184844
F20328
NCGC00258947-01
5-Acetamido-o-anisidine
6-methoxy-3-acetylamino-aniline
2-Amino-4-(acetylamino)anisole
N1-Acetyl-4-methoxy-1,3-phenylenediamine
F2190-0483
Amino-4'-methoxyacetanilide, 3'-
2-Amino-4-acetylaminoanisole
6375-47-9
Tox21_303427
FT-0614980
2-Amino-4-(acetylamino)phenyl methyl ether
CAS-6375-47-9
N-(3-amino-4-methoxy-phenyl)acetamide
1-Methoxy-4-(N-acetylamino)-2-aminobenzene
TIMTEC-BB SBB000217
DTXCID507620
DTXSID2027620
2-Amino-4-acetamidoanisole
4-Acetamino-2-aminoanisole
FSR7TUQ7VK
3'-Amino-4'-methoxyacetoanilide
2-Amino-4-acetamino anisole
2-Methoxy-5-acetamidoaniline
NCGC00257450-01
N-(3-Amino-4-methoxyphenyl)acetamide #
CS-W017195
3-Amino-4-methoxyacetanilide
3-Amino-4-Methoxy Acetanilide

MDL Number

MFCD00008676

Customs Code

2924299090

FAQ

What are the physical and chemical properties of N-(3-Amino-4-methoxyphenyl)acetamide (CAS: 6375-47-9)?

N-(3-Amino-4-methoxyphenyl)acetamide is a white crystalline solid with a molecular weight of approximately 227.26 g/mol. It is moderately soluble in water and has good solubility in organic solvents. The compound is relatively stable under normal conditions but may react with strong acids to form amide derivatives.

How is N-(3-Amino-4-methoxyphenyl)acetamide (CAS: 6375-47-9) typically synthesized?

N-(3-Amino-4-methoxyphenyl)acetamide is typically synthesized by reacting 3-amino-4-methoxyaniline with acetic anhydride using a base like sodium hydroxide. The reaction is carried out in a solvent like ethanol, yielding a pure product with high selectivity and good yield.

What industries use N-(3-Amino-4-methoxyphenyl)acetamide (CAS: 6375-47-9)?

N-(3-Amino-4-methoxyphenyl)acetamide finds use in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the production of polymer additives and as a precursor in chemical sensors and semiconductors due to its functional groups.

What precautions should be taken when handling N-(3-Amino-4-methoxyphenyl)acetamide (CAS: 6375-47-9)?

When handling N-(3-Amino-4-methoxyphenyl)acetamide, it is important to use personal protective equipment (PPE) such as gloves and safety goggles. Store the compound in a cool, dry place and use a fume hood during operations. In case of spills, clean up immediately using appropriate absorbents and consult a safety data sheet (SDS) for detailed instructions.