3,3-Difluorocyclobutanol

Basic Information

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CAS Number

637031-88-0

Molecular Formula

C4H6F2O

Molecular Weight

108.09 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Density

1.3

Refractive Index

1.39

SMILES

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C1C(CC1(F)F)O

InChI

InChI=1S/C4H6F2O/c5-3-1-2-4(3,6)7/h3,7H,1-2H2

InChIKey

FKZSRMIGRHPTKT-UHFFFAOYSA-N

LogP

0.7764

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

73.8

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

3,3-Difluorocyclobutanol
1-(2-(difluoromethyl)phenyl)ethanol
3,3-difluorocyclobutan-1-ol
3,3-Difluoro-cyclobutanol
CYCLOBUTANOL, 3,3-DIFLUORO-
BFLCYDVYEGKWSQ-UHFFFAOYSA-N
STL556311
BBL102508
FCH995685
PB30337
SY035859
PC420013
ST1110761
AB0025979
AX8208932
W7555
3,3-DIFLUOROCYCLOBUTAN-1-OL
A852804
3,3-difluorocyclobutanol
EN300-316700
AMY14724
DB-073380
AS-18466
MFCD18791191
MFCD10000932
SCHEMBL1808769
AKOS015856477
CS-W000105
IIZFUVHUFRJSKY-UHFFFAOYSA-N
637031-88-0
DTXSID30626277

MDL Number

MFCD18791191

FAQ

What are the physical and chemical properties of 3,3-Difluorocyclobutanol (CAS: 637031-88-0)?

3,3-Difluorocyclobutanol is a colorless liquid with a molecular weight of 98.05 g/mol. It has a solubility of 3.3 g/L in water and is slightly soluble in ethanol. Chemically, it is highly reactive towards nucleophiles and can undergo substitution reactions. It is used as a precursor in organic synthesis and exhibits good reactivity in Wittig reactions.

How is 3,3-Difluorocyclobutanol (CAS: 637031-88-0) typically synthesized?

3,3-Difluorocyclobutanol is typically synthesized through the reaction of cyclobutanol with fluorine gas in the presence of an appropriate catalyst, such as copper(II) fluoride. The process provides good selectivity and yield, with the reaction being conducted under anhydrous conditions to prevent side reactions.

What industries use 3,3-Difluorocyclobutanol (CAS: 637031-88-0)?

3,3-Difluorocyclobutanol is primarily used in the pharmaceutical industry for the synthesis of complex organic molecules. It is also utilized in the polymer industry for the modification of polymers and in the semiconductor industry for the production of photoresists and other chemical materials. Additionally, it finds applications in the production of sensors and other advanced materials.

What precautions should be taken when handling 3,3-Difluorocyclobutanol (CAS: 637031-88-0)?

Handling 3,3-Difluorocyclobutanol should be done with appropriate personal protective equipment (PPE), including safety glasses and gloves. It should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, the area should be ventilated and the spill cleaned up using appropriate absorbents. Safety data sheets (SDS) should be consulted for detailed handling and emergency procedures.