6,7-Dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride_x000D_

Basic Information

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CAS Number

63590-64-7

Molecular Formula

C19H25N5O4

Molecular Weight

387.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

281-283°C

Boiling Point

664.5 °C at 760 mmHg

Density

1.332

Flash Point

355.7 °C

Solubility

H2O: 25 mg/mL

SMILES

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COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC

InChI

InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)

InChIKey

VCKUSRYTPJJLNI-UHFFFAOYSA-N

LogP

pKa

pKa (0.1N NaOH): 7.1(at 25℃)

Complexity

544

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

AC-11120
NCGC00025191-03
Vasomet
6,7-Dimethoxy-2-[4-(tetrahydro-2-furanylcarbonyl)-1-piperazinyl]-4-quinazolinamine #
Prestwick3_000751
Terazosina (INN-Spanish)
Terazosina [INN-Spanish]
6,7-dimethoxy-2-(4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl)quinazolin-4-amine
Terazosabb (TN)
DTXCID003639
D08569
Q280786
HMS2232N21
6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine
L000692
terazosin a
Terazosine (INN-French)
Prestwick2_000751
6,7-bis(methyloxy)-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine
BRD-A22256192-003-14-4
EN300-119614
1-(4-amino-6,7-dimethoxyquinazolin-2-yl)-4-[[(2RS)-2,3,4,5-tetrahydrofuran-2-yl]carbonyl]piperazine
Prestwick0_000751
SMR000058309
C19H25N5O4
6,7-dimethoxy-2-{4-[(oxolan-2-yl)carbonyl]piperazin-1-yl}quinazolin-4-amine
REGID_for_CID_5401
HMS3371E20
HMS2090P21
terazosin
DTXSID3023639

MDL Number

MFCD00072144

FAQ

What regulatory guidelines apply to 6,7-Dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride (CAS: 63590-64-7)?

The compound is subject to GHS classification, REACH regulations, and FDA/EPA related requirements for safety and environmental handling. Regulatory compliance includes MSDS preparation, proper labeling, and documentation for transport and disposal.

Are there alternatives to 6,7-Dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride (CAS: 63590-64-7) in synthesis?

Alternatives may include related analogs such as 6,7-dimethoxyquinazoline derivatives or different piperazinyl moieties. Common alternative reagents include different carboxylic acids or amines, but these will vary based on the specific synthetic goal.

What is the market or research trend for 6,7-Dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride (CAS: 63590-64-7)?

The market trend shows growing interest in this compound for its potential in antiviral and anti-inflammatory applications. Research is focusing on its pharmacological properties and potential therapeutic uses, with increasing publications and patents related to its development.

How should waste containing 6,7-Dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride (CAS: 63590-64-7) be handled?

Waste containing the compound should be collected in appropriate containers, labeled, and stored in a secure area. Proper incineration or professional waste disposal services should be used. Always follow local regulations and guidelines to ensure environmental safety and compliance.