Dihydrocyclosporin C

Basic Information

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CAS Number

63556-15-0

Molecular Formula

C62H113N11O13

Molecular Weight

1220.65 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.033±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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CCCC[C@@H](C)[C@H]([C@H]1C(=O)N[C@H](C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)[C@@H](C)O)O

InChI

InChI=1S/C62H113N11O13/c1-25-26-27-39(14)52(76)51-56(80)66-49(42(17)74)60(84)67(18)32-47(75)68(19)43(28-33(2)3)55(79)65-48(37(10)11)61(85)69(20)44(29-34(4)5)54(78)63-40(15)53(77)64-41(16)57(81)70(21)45(30-35(6)7)58(82)71(22)46(31-36(8)9)59(83)72(23)50(38(12)13)62(86)73(51)24/h33-46,48-52,74,76H,25-32H2,1-24H3,(H,63,78)(H,64,77)(H,65,79)(H,66,80)/t39-,40+,41-,42-,43+,44+,45+,46+,48+,49+,50+,51+,52-/m1/s1

InChIKey

QHSAVIYJLPPRIS-YRQGTVDASA-N

LogP

2.4638

Topological Polar Surface Area

299.03000000000003 Å²

Hydrogen Bond Donor/Acceptor

6 / 24

Synonyms & References

English

Cyclosporin C,6-[(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)octanoic acid]- (9CI)
24-tert-butyl-30-(1-hydroxyethyl)-33-(1-hydroxy-2-methylhexyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacon
DIHYDROXYCLOSPORIN C
Cyclosporin A,6-((3R,4R)-3-hydroxy-N,4-dimethyl-L-2-aminooctanoic acid)-7-L-threonine
Cyclosporin A,6-((R-(R*,R*))-3-hydroxy-N,4-dimethyl-L-2-aminooctanoic acid)-7-L-threonine
DIHYDROCYCLOSPORIN C
Cyclosporin Impurity 13（Dihydrocyclosporin C）
Cyclosporin A, 6-[(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)octanoic acid]-7-L-threonine-
Cyclosporine Impurity 13

FAQ

What regulatory guidelines apply to Dihydrocyclosporin C (CAS: 63556-15-0)?

Dihydrocyclosporin C (CAS: 63556-15-0) is classified under GHS as a skin sensitiser and reproductive toxin. It is subject to REACH regulations in the EU, which require registration, evaluation, and authorization for substances of more than 1 tonne per year. FDA and EPA guidelines must also be adhered to for import and use in the USA, focusing on safety data sheets, risk assessments, and environmental impacts.

Are there alternatives to Dihydrocyclosporin C (CAS: 63556-15-0) in synthesis?

Alternative analogs such as dihydrocyclosporin D can be used in synthesis. Isomers like (R)- and (S)-Dihydrocyclosporin C are also available. Common reagents for synthesis include N-methylmorpholine N-oxide (NMMO) and other oxidants, which can serve as effective substitutes.

What is the market or research trend for Dihydrocyclosporin C (CAS: 63556-15-0)?

The market trend for Dihydrocyclosporin C (CAS: 63556-15-0) shows growing interest in its immunosuppressive properties. Research is focusing on its potential in treating autoimmune diseases and improving drug delivery systems. Price trends are stable, with increasing demand from pharmaceutical and academic research sectors.

How should waste containing Dihydrocyclosporin C (CAS: 63556-15-0) be handled?

Waste containing Dihydrocyclosporin C (CAS: 63556-15-0) should be collected in sealed containers and disposed of through professional waste disposal services. Incineration is recommended for safe disposal, following local environmental protection regulations. Protective measures such as gloves and masks must be worn during handling to prevent exposure and ensure environmental safety.