3-Bromo-1H-pyrazolo[4,3-c]pyridine

Basic Information

View in Editor

CAS Number

633328-88-8

Molecular Formula

C6H4BrN3

Molecular Weight

198.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

White to Yellow Solid

Density

1.894

SMILES

View in Editor

C1=CN=CC2=C(NN=C21)Br

InChI

InChI=1S/C6H4BrN3/c7-6-4-3-8-2-1-5(4)9-10-6/h1-3H,(H,9,10)

InChIKey

NUCFNMOPTGEHQA-UHFFFAOYSA-N

LogP

1.7204

Topological Polar Surface Area

41.57 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

130

Safety Information

View Safety Information

GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

633328-88-8
CS-W008912
MFCD11518973
J-511807
AKOS006323464
AC-23304
AM20061848
PB20592
FT-0646414
DTXSID00671931
3-Bromo-1H-pyrazolo[4,3-c]pyridine, AldrichCPR
SY008427
3-bromo-2H-pyrazolo[4,3-c]pyridine
3-Bromopyrazolo[4,3-c]pyridine
A834334
DIISOOCTYLAZELATE
3-BROMO-1H-PYRAZOLO[4,3-C]PYRIDINE
FS-2880
NUCFNMOPTGEHQA-UHFFFAOYSA-N
SCHEMBL4145343
3-Bromo-1H-pyrazolo[4,3-c]pyridine
1H-Pyrazolo[4,3-c]pyridine,3-bromo-
3-Bromo-5-azaindazole
3-BROMO-5-AZA-1H-INDAZOLE
PubChem14717
1H-Pyrazolo[4,3-c]pyridine, 3-bromo-
5-AZA-3-BROMO-1H-INDAZOLE
FCH894355
CB0250
OR30699
VP13126

MDL Number

MFCD11518973

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 3-Bromo-1H-pyrazolo[4,3-c]pyridine (CAS: 633328-88-8)?

3-Bromo-1H-pyrazolo[4,3-c]pyridine is a crystalline solid with a molecular weight of approximately 237.03 g/mol. It is slightly soluble in water and more soluble in organic solvents like DMSO and DMF. This compound shows moderate reactivity, particularly towards nucleophiles, and exhibits good stability under normal storage conditions.

How is 3-Bromo-1H-pyrazolo[4,3-c]pyridine (CAS: 633328-88-8) typically synthesized?

3-Bromo-1H-pyrazolo[4,3-c]pyridine is commonly synthesized via bromination of 1H-pyrazolo[4,3-c]pyridine using N-bromosuccinimide (NBS) in the presence of a peroxide initiator like benzoyl peroxide. The reaction yields the desired product with good selectivity and moderate yield.

What industries use 3-Bromo-1H-pyrazolo[4,3-c]pyridine (CAS: 633328-88-8)?

3-Bromo-1H-pyrazolo[4,3-c]pyridine finds applications in pharmaceuticals, particularly as a precursor for drug synthesis. It is also used in the preparation of sensors and as a ligand in coordination chemistry, though its uses in other industries are more limited.

What precautions should be taken when handling 3-Bromo-1H-pyrazolo[4,3-c]pyridine (CAS: 633328-88-8)?

When handling 3-Bromo-1H-pyrazolo[4,3-c]pyridine, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood, and ensure proper spill cleanup procedures are followed. Always consult the Safety Data Sheet (SDS) for detailed safety information.