[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)methanone hydrochloride (1:1)

Basic Information

View in Editor

CAS Number

63074-08-8

Molecular Formula

C19H26ClN5O4

Molecular Weight

423.9 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Water Solubility

Soluble in water at 20mg/ml. Also soluble in methanol or ethanol.

Solubility

H2O: 25 mg/mL

SMILES

View in Editor

COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC.Cl

InChI

InChI=1S/C19H25N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H

InChIKey

IWSWDOUXSCRCKW-UHFFFAOYSA-N

LogP

1.4785999999999995

Topological Polar Surface Area

103.04 Å²

Hydrogen Bond Donor/Acceptor

2 / 9

Complexity

544

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

DTXSID7045493
EN300-122363
HY-B0371F
BCP12795
TERAZOSIN HYDROCHLORIDE ANHYDROUS [WHO-DD]
D70611
Terazocin Hydrochloride (anhydrous)
Tox21_110674_1
Q27270906
MLS001077301
ABBOTT-45975 ANHYDROUS
FT-0605647
6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride
s4679
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-, monohydrochloride
NSC-759168
Prestwick_146
EU-0101138
NSC759168
SR-01000000197
TERAZOSIN HYDROCHLORIDE (USP-RS)
TERAZOSIN HYDROCHLORIDE, ANHYDROUS
MFCD00467965
Zayasel
NCGC00016026-10
CHEBI:9446
1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)-piperazine hydrochloride
MLS001305722
CHEMBL1256665
4-Amino-6,7-dimethoxy-2-[4-(tetrahydro-2-furoyl)-1-piperazinyl]quinazoline Hydrochloride
TERAZOSIN HYDROCHLORIDE [MI]

MDL Number

MFCD00467965

FAQ

What is [compound name] (CAS: 63074-08-8)?

4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl-(tetrahydro-2-furanyl)methanone hydrochloride (1:1), also known as MZ426 hydrochloride, is a complex organic compound with a molecular structure combining a quinazoline derivative, piperazine, furan, and a hydrochloride moiety. It has a characteristic chemical formula and is characterized by its low volatility and stability under normal conditions.

What are the main uses of [compound name] (CAS: 63074-08-8)?

MZ426 hydrochloride (CAS: 63074-08-8) is primarily used in the pharmaceutical industry as an intermediate or potential drug candidate for the treatment of various diseases, including but not limited to inflammatory and autoimmune conditions. It is also used in research for investigating the biological properties of quinazoline derivatives.

Is [compound name] (CAS: 63074-08-8) safe?

The safety of MZ426 hydrochloride depends on proper handling. It is not classified as a toxic substance, but exposure to the eyes, skin, or ingestion can cause irritation. It is recommended to handle it with gloves and lab coats, and to avoid contact with eyes and skin. Storage and use should comply with standard safety measures for organic compounds.

How should [compound name] (CAS: 63074-08-8) be stored?

MZ426 hydrochloride (CAS: 63074-08-8) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in tightly sealed containers to protect against moisture and air. The temperature should be maintained below 25°C, and humidity levels should be kept low to ensure stability and prevent degradation.