ent-Tadalafil | CAS No. 629652-72-8

ent-Tadalafil

Basic Information

View in Editor

CAS Number

629652-72-8

Molecular Formula

C22H19N3O4

Molecular Weight

389.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Density

1.51±0.1 g/cm3 (20 ºC 760 Torr),

Solubility

Insuluble (8.6E-3 g/L) (25 ºC),

SMILES

View in Editor

CN1CC(=O)N2C(C1=O)CC3=C(C2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36

InChI

InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m0/s1

InChIKey

WOXKDUGGOYFFRN-KKSFZXQISA-N

LogP

2.2112999999999996

Topological Polar Surface Area

74.87 Å²

Hydrogen Bond Donor/Acceptor

1 / 7

Complexity

702

Synonyms & References

English

ent-Tadalafil
(6S,12aS)-tadalafil
ENT-TADALAFIL,WHITE SOLID
Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3- benzodioxol-5-yl)-2,3,6,7,12, 12a-hexahydro-2-methyl-,(6S, 12...
L-Tadalafil
L-Tildenafil
UNII-HZ6QJN0D4Z
(6S,12S)-Tadalafil
(6S,12aS)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
(2S,8S)-2-(1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
CHEMBL344855
Q27280173
HY-90009C
(2S,8S)-2-(1,3-dioxaindan-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11(16),12,14-tetraene-4,7-dione
Tadalafil impurity B [EP]
(6S ,12as)-tadalafil
(6S,12aS)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
ent-IC-351
CS-0092070
EN300-20237865
629652-72-8
BDBM50134134
HZ6QJN0D4Z
C16117
(6S ,12As )-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b )indole-1,4-dione
(6S,12aS)-6-(benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
Pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6S,12aS)-
SCHEMBL7440401
AKOS030529164
(6S,12aS)-6-(1,3-Benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
(-)-TRANS-TADALAFIL

MDL Number

MFCD23380729

FAQ

What is ent-Tadalafil (CAS: 629652-72-8)?

Ent-Tadalafil is a selective phosphodiesterase type 5 (PDE5) inhibitor with a compact molecular structure and a unique conformation. It is widely known for its pharmaceutical applications, particularly in the treatment of erectile dysfunction and benign prostatic hyperplasia.

What are the main uses of ent-Tadalafil (CAS: 629652-72-8)?

Ent-Tadalafil is primarily used in the treatment of erectile dysfunction and benign prostatic hyperplasia. It is also used in clinical research for its PDE5 inhibitory properties.

Is ent-Tadalafil (CAS: 629652-72-8) safe?

Ent-Tadalafil is generally considered safe when used as directed. However, it is important to follow medical advice to avoid potential side effects and interactions with other medications. Patients should consult a healthcare provider if they experience any adverse reactions.

How should ent-Tadalafil (CAS: 629652-72-8) be stored?

Ent-Tadalafil should be stored in a cool, dry place, away from direct sunlight and moisture. It is recommended to keep it in its original container to protect it from light and maintain its efficacy. Avoid storing it in temperatures above 25°C (77°F).