(5Z)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione | CAS No. 627502-58-3

(5Z)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione

Basic Information

CAS Number

627502-58-3

Molecular Formula

C19H18N2O3S

Molecular Weight

354.43 g/mol

EINECS

145-896-5

AD

Basic Physical Properties

Melting Point

156-160 °C

CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)C=C3C(=O)NC(=O)S3

InChI

InChI=1S/C19H18N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,11-12H,2,9-10H2,1H3,(H,21,22,23)/b17-11-

InChIKey

YNTUJOCADSTMCL-BOPFTXTBSA-N

LogP

3.589400000000002

Topological Polar Surface Area

68.28999999999999 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

515

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • (E)-5-{4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzylidene}thiazolidine- 2,4-dione
  • 2,4-Thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methylene)-, (5Z)-
  • SCHEMBL2002766
  • 136401-69-9
  • SCHEMBL2002770
  • Didehydropioglitazone, (5Z)-
  • (5Z)-5-((4-(2-(5-Ethylpyridin-2-yl)ethoxy)phenyl)methylene)thiazolidine-2,4-dione
  • 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzylidene]-2,4-Thiazolidinedione
  • AC-4718
  • Pioglitazone hydrochloride specified impurity B [EP]
  • PIOGLITAZONE HYDROCHLORIDE IMPURITY, DIDEHYDROPIOGLITAZONE- [USP IMPURITY]
  • PIOGLITAZONE HYDROCHLORIDE IMPURITY B [EP IMPURITY]
  • 5-{4-[2-(5-ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione;5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione
  • AKOS015964231
  • AS-13104
  • UNII-6SE873CO82
  • Pioglitazone hydrochloride impurity, didehydropioglitazone- [USP]
  • 627502-58-3
  • (5Z)-didehydropioglitazone
  • (5Z)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione
  • Q27265442
  • 5-[[4-[2-(5-ethyl-2-pyridinyl)-ethoxy]phenyl]methylene]-2,4-thiazolidinedione
  • (Z)-5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione
  • 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-
  • A3141
  • 5-[4-[2-(5-Ethyl-2-Pyridyl)Ethoxy]-2-Imino-4-Thiazoldione
  • 5-[4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzylidene]-2,4-thiazolidinedione
  • 6SE873CO82
  • 2,4-THIAZOLIDINEDIONE, 5-[[4-[2-(5-ETHYL-2-PYRIDINYL)ETHOXY]PHENYL]METHYL]-, DIDEHYDRO
  • 5-[[4-[2-(5-Ethyl-2-pyridinyl)
  • 5-[(E)-[4-[2-(5-ETHYL-2-PYRIDINYL)ETHOXY]PHENYL]METHYLENE]-2,4-THIAZOLIDINEDIONE

MDL Number

MFCD06411145

EC Number

145-896-5

FAQ

What is (5Z)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione (CAS: 627502-58-3)?

This compound is a thiazolidine derivative with a complex structure. It is characterized by its Z-isomer and includes an ethyl-substituted pyridine group. It is a white to light yellow crystalline solid with a molecular weight of approximately 500 g/mol.

What are the main uses of (5Z)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione (CAS: 627502-58-3)?

This compound is primarily used in pharmaceutical research for potential anti-inflammatory and antitumor applications. It may also find use in organic synthesis as a building block for more complex compounds.

Is (5Z)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione (CAS: 627502-58-3) safe?

While generally safe for laboratory use, this compound should be handled with caution due to its potential for skin and respiratory irritation. Adequate personal protective equipment (PPE) including gloves and goggles is recommended. Proper ventilation is also necessary to avoid inhalation risks.

How should (5Z)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione (CAS: 627502-58-3) be stored?

Store this compound in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation. Ideal storage conditions are between 15-25°C (59-77°F) and below 60% relative humidity.

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