Ethoxyacetic acid

Basic Information

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CAS Number

627-03-2

Molecular Formula

C4H8O3

Molecular Weight

104.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

207°C

Density

1.102 g/mL at 25 °C

Refractive Index

n20/D 1.419(lit.)

SMILES

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CCOCC(=O)O

InChI

InChI=1S/C4H8O3/c1-2-7-3-4(5)6/h2-3H2,1H3,(H,5,6)

InChIKey

YZGQDNOIGFBYKF-UHFFFAOYSA-N

LogP

0.1075000000000001

pKa

3.65(at 18℃)

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

Safety Information

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Hazard Statement

H290 May be corrosive to metals
Corrosive to Metals

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Stability

Stable. Combustible. Incompatible with strong oxidizing agents.

Synonyms & References

English

NSC6750
NCGC00090711-02
EN300-21303
ETHOXYACETIC ACID (EGMEE (110-80-5))
Z104495232
Glycolic acid ethyl ether
O-Ethylglycolic acid
MFCD00004310
2-ethoxy-acetic acid
E0377
Tox21_303384
CS-0071579
UNII-467VW095BX
A833937
D73862
NCGC00259980-01
Acetic acid, 2-ethoxy-
CAS-627-03-2
AI3-24145
SCHEMBL48574
Ethoxyacetic acid, purum, >=98.0% (GC)
Ethoxy acetic acid
CCRIS 7194
NSC 6750
Ethoxy-acetic acid anion
CHEMBL1159929
CHEBI:173365
STR05191
YZGQDNOIGFBYKF-UHFFFAOYSA-
2-Ethoxyacetic acid
AMY4062

MDL Number

MFCD00004310

Customs Code

2918990090

FAQ

What are the physical and chemical properties of Ethoxyacetic acid (CAS: 627-03-2)?

Ethoxyacetic acid (CAS: 627-03-2) is a colorless to pale yellow liquid with a molecular weight of 118.15 g/mol. It has a pKa of approximately 4.4 and is moderately soluble in water. Chemically, it is reactive and can undergo esterification and substitution reactions, making it useful in various applications.

How is Ethoxyacetic acid (CAS: 627-03-2) typically synthesized?

Ethoxyacetic acid (CAS: 627-03-2) can be synthesized via the reaction of ethyl acetate with hydrochloric acid. This process involves acetylation of ethanol followed by hydrolysis, yielding the desired acid. The reaction typically proceeds with good yield and can be catalyzed by acids such as hydrochloric acid.

What industries use Ethoxyacetic acid (CAS: 627-03-2)?

Ethoxyacetic acid (CAS: 627-03-2) is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry for modifying polymer properties, and in the chemical industry for producing various organic compounds. It also finds applications in the food industry as a flavor enhancer and in the manufacturing of sensors and semiconductors.

What precautions should be taken when handling Ethoxyacetic acid (CAS: 627-03-2)?

When handling Ethoxyacetic acid (CAS: 627-03-2), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. It should be stored in a cool, well-ventilated area away from direct sunlight. In case of spills, use appropriate absorbents and handle according to the material safety data sheet (MSDS). Always ensure proper ventilation and use a fume hood when performing operations that may release vapors.