Azacitidine Impurity 40

Basic Information

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CAS Number

62488-57-7

Molecular Formula

C8H14N4O5

Molecular Weight

246.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

529.1°C at 760 mmHg

Density

2.10±0.1 g/cm3 (20 ºC 760 Torr),

Flash Point

273.8°C

Refractive Index

1.823

SMILES

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NC1=NC(=O)N(CN1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

InChI

InChI=1S/C8H14N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h3-6,13-15H,1-2H2,(H3,9,10,11,16)/t3-,4-,5-,6-/m1/s1

InChIKey

LJIRBXZDQGQUOO-KVTDHHQDSA-N

LogP

-3.2771999999999983

Topological Polar Surface Area

140.64000000000001 Å²

Hydrogen Bond Donor/Acceptor

6 / 9

Complexity

349

Synonyms & References

English

1,3,5-Triazin-2(1H)-one,4-amino-3,6-dihydro-1-b-D-ribofuranosyl-
5,6-Dihydro-5-azacytidine
5,6 dihydro-5-azacytidine
Ccris 6743
DHAC
Dihydro-5-azacytidine
NSC 264-880
NSC 26480
NSC 265483
{ "\"0\"": "DHAC" }
{ "\"1\"": " Dihydro-5-azacytidine" }
{ "\"2\"": " NSC 264-880" }
{ "\"3\"": " NSC 26480" }
{ "\"4\"": " NSC 265483" }

MDL Number

MFCD00800370

FAQ

What regulatory guidelines apply to Azacitidine Impurity 40 (CAS: 62488-57-7)?

Azacitidine Impurity 40 (CAS: 62488-57-7) is regulated under various international guidelines such as GHS for hazard communication, REACH for European Union registration, and FDA and EPA for environmental and safety standards. Manufacturers must comply with these regulations for proper labeling, handling, and disposal.

Are there alternatives to Azacitidine Impurity 40 (CAS: 62488-57-7) in synthesis?

In the synthesis of azacitidine, alternatives to Azacitidine Impurity 40 (CAS: 62488-57-7) include using higher purity azacitidine or other similar purities. Other reagents like azido compounds or precursors can also be considered as substitutes, depending on the specific synthesis requirements and desired product purity.

What is the market or research trend for Azacitidine Impurity 40 (CAS: 62488-57-7)?

Market trends for Azacitidine Impurity 40 (CAS: 62488-57-7) reflect an increase in research and development activities for cancer treatments, particularly targeting azacitidine-based therapies. Emerging research focuses on improving drug efficacy and reducing impurity levels to enhance product quality and safety.

How should waste containing Azacitidine Impurity 40 (CAS: 62488-57-7) be handled?

Waste containing Azacitidine Impurity 40 (CAS: 62488-57-7) should be collected in appropriate containers and stored separately to avoid contamination. Incineration or professional waste disposal services are recommended for proper disposal to ensure environmental safety and compliance with local regulations. Always follow safety protocols and consult local environmental authorities for specific disposal requirements.