MK-0812 | CAS No. 624733-88-6

MK-0812

Basic Information

CAS Number

624733-88-6

Molecular Formula

C24H34F3N3O3

Molecular Weight

469.54 g/mol

AD

Basic Physical Properties

Density

1.24

CC(C)C1(CCC(C1)NC2CCOCC2OC)C(=O)N3CCC4=C(C3)C=C(C=N4)C(F)(F)F

InChI

InChI=1S/C24H34F3N3O3/c1-15(2)23(7-4-18(11-23)29-20-6-9-33-14-21(20)32-3)22(31)30-8-5-19-16(13-30)10-17(12-28-19)24(25,26)27/h10,12,15,18,20-21,29H,4-9,11,13-14H2,1-3H3/t18-,20+,21-,23+/m1/s1

InChIKey

MTMDXAIUENDNDL-RJSMDTJLSA-N

LogP

3.573500000000001

Topological Polar Surface Area

63.690000000000005 Ų

Hydrogen Bond Donor/Acceptor

1 / 6

Complexity

692

Synonyms & References

English

  • MK-0812
  • [(1S,3R)-3-[[(3S,4S)-3-methoxyoxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[3-(trifluoromethyl)-7,8-dihydro-5H-1,6-naphthyridin-6-yl]methanone
  • 1,5-Anhydro-2,3-dideoxy-3-[[(1R,3S)-3-[[7,8-dihydro-3-(trifluoromethyl)-1,6-naphthyridin-6(5H)-yl]carbonyl]-3-(1-methylethyl)cyclopentyl]amino]-4-O-methyl-D-erythro-pentitol
  • D-erythro-Pentitol, 1,5-anhydro-2,3-dideoxy-3-[[(1R,3S)-3-[[7,8-dihydro-3-(trifluoromethyl)-1,6-naphthyridin-6(5H)-yl]carbonyl]-3-(1-methylethyl)cyclopentyl]amino]-4-O-methyl-
  • MK 0812
  • ((1R,3S)-3-isopropyl-3-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopentyl)[(3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl]amine
  • CS-0344
  • N-((1R,3S)-3-isopropyl-3-[[3-trifluoromethyl-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl]-cyclopentyl)-N-[(3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl]-amine
  • BCPP000160
  • GTPL9048
  • NCGC00378765-04
  • AKOS025401941
  • SCHEMBL2209755
  • BCP9000945
  • MTMDXAIUENDNDL-RJSMDTJLSA-N
  • 624733-88-6
  • CHEMBL3305901
  • AS-32918
  • BRD-K14175878-001-01-6
  • NCGC00378765-03
  • (3S,4S)-N-[(1R,3S)-3-ISOPROPYL-3-[3-(TRIFLUOROMETHYL)-7,8-DIHYDRO-5H-1,6-NAPHTHYRIDINE-6-CARBONYL]CYCLOPENTYL]-3-METHOXYOXAN-4-AMINE
  • NCGC00378765-02
  • HY-50669
  • ((1S,3R)-1-isopropyl-3-(((3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl)amino)cyclopentyl)(3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)methanone
  • (3S,4S)-N-[(1R,3S)-3-isopropyl-3-{[3-(trifluoromethyl)-7,8-dihydro-5H-1,6-naphthyridin-6-yl]carbonyl}cyclopentyl]-3-methoxyoxan-4-amine
  • EX-A939
  • 1,5-Anhydro-2,3-dideoxy-3-[[(1R,3S)-3-[[7,8-dihydro-3-(trifluoromethyl)-1,6-naphthyridin-6(5H)-yl]carbonyl]-3-(1-methylethyl)cyclope ntyl]amino]-4-O-methyl-D-erythro-pentitol
  • AC-27464
  • J-504013
  • BDBM50077906
  • Q27086701

MDL Number

MFCD11977737

FAQ

What are the physical and chemical properties of MK-0812 (CAS: 624733-88-6)?

MK-0812 is a白色结晶性固体,具有较高的熔点。分子量约为500。在水中溶解度较低,在有机溶剂中具有一定的溶解性。化学性质相对稳定,在酸碱条件下表现出一定的反应性。

How is MK-0812 (CAS: 624733-88-6) typically synthesized?

MK-0812通常通过多步合成反应制备,包括官能团转化和连接反应。常用的催化剂包括过渡金属催化剂,反应的收率可以达到80%以上。

What industries use MK-0812 (CAS: 624733-88-6)?

MK-0812主要应用于制药行业,作为潜在的抗癌药物候选物。此外,它还可以用于合成其他有机化合物。

What precautions should be taken when handling MK-0812 (CAS: 624733-88-6)?

在处理MK-0812时,应佩戴个人防护装备,包括手套和防护眼镜。应在通风橱中操作,避免吸入粉尘。如果发生泄漏,应立即清理并参考安全数据表(SDS)进行处理。

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