Oxetan-3-ylmethanamine

Basic Information

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CAS Number

6246-05-5

Molecular Formula

C4H9NO

Molecular Weight

87.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

131°C at 760 mmHg

Density

1.014 g/mL at 25 °C

Refractive Index

n20/D 1.458

Vapor Pressure

9.5±0.2 mmHg at 25°C

SMILES

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C1C(CO1)CN

InChI

InChI=1S/C4H9NO/c5-1-4-2-6-3-4/h4H,1-3,5H2

InChIKey

KTHZBRAXOLUNBN-UHFFFAOYSA-N

LogP

-0.4085000000000001

Topological Polar Surface Area

35.25 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

42.8

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Air Sensitive

Synonyms & References

English

Oxetan-3-ylmethanamine
3-Aminomethyloxetane
3-Aminomethyl-oxetane
1-(Oxetan-3-yl)methanamine
3-Oxetanemethanamine
(Oxetan-3-yl)methanamine
oxetan-3-ylmethamine
Oxetane-3-methanamine
oxetane-3-ylmethanamine
PubChem23208
N-Methyl-3-oxetanamne
3-(Aminomethyl)oxetane
1-(3-Oxetanyl)methanamine
KTHZBRAXOLUNBN-UHFFFAOYSA-N
C-OXETAN-3-YL-METHYLAMINE
HT447
HT766
CO0046
BBL102067
STL555866
AN
3-oxetanemethanamine
PB26850
DB-264671
SY025447
MFCD12547197
AKOS006345693
DB-073124
6246-05-5
EN300-188212
J-512990

MDL Number

MFCD12547197

FAQ

What are the physical and chemical properties of Oxetan-3-ylmethanamine (CAS: 6246-05-5)?

Oxetan-3-ylmethanamine (CAS: 6246-05-5) is a colorless liquid with a molecular weight of 115.15 g/mol. It has a pKa of about 10.6, indicating basic properties. The compound is moderately soluble in water and highly soluble in organic solvents such as ethanol and acetone. It is known for its reactivity towards nucleophiles and can undergo substitution reactions. It has a mild odor and is stable under normal conditions but should be stored in a cool, dry place away from heat sources.

How is Oxetan-3-ylmethanamine (CAS: 6246-05-5) typically synthesized?

Oxetan-3-ylmethanamine (CAS: 6246-05-5) is typically synthesized through the reaction of oxetane with methylamine. The process involves the addition of methylamine to oxetane in the presence of a base such as potassium carbonate. The reaction can be performed in anhydrous conditions to improve yield. Key factors include the reaction temperature and the use of a solvent like dimethylformamide (DMF) to enhance reactivity.

What industries use Oxetan-3-ylmethanamine (CAS: 6246-05-5)?

Oxetan-3-ylmethanamine (CAS: 6246-05-5) finds applications in the pharmaceutical industry for the synthesis of certain drugs and as a molecular scaffold. It is also used in the polymer industry as an amine curing agent for epoxy resins. Additionally, it has applications in the semiconductor industry as a dopant and in sensors for its reactivity with various analytes. Its use in these industries leverages its unique chemical properties.

What precautions should be taken when handling Oxetan-3-ylmethanamine (CAS: 6246-05-5)?

When handling Oxetan-3-ylmethanamine (CAS: 6246-05-5), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from heat and open flames. It should be used in a well-ventilated area or a fume hood to minimize exposure. In case of spills, the area should be evacuated and the spill cleaned up with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.