2-(Ethoxymethyl)tetrahydrofuran

Basic Information

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CAS Number

62435-71-6

Molecular Formula

C7H14O2

Molecular Weight

130.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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CCOCC1CCCO1

InChI

InChI=1S/C7H14O2/c1-2-8-6-7-4-3-5-9-7/h7H,2-6H2,1H3

InChIKey

VUFKMYLDDDNUJS-UHFFFAOYSA-N

LogP

1.2019

Topological Polar Surface Area

18.46 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

73.3

Synonyms & References

English

62435-71-6
2-(ethoxymethyl)oxolane
NSC 93907
AI3-30797
tetrahydrofurfuryl ethyl ether
AKOS006275715
DTXSID00886169
NSC93907
SCHEMBL1002690
MFCD00086162
NSC-93907
Furan, 2-(ethoxymethyl)tetrahydro-
NS00007293
ethyltetrahydrofurfuryl ether
2-(ethoxymethyl)tetrahydrofuran
Ethyl tetrahydrofurfuryl ether
Ethyltetrahydrofurfurylether
FT-0654746
2-(Ethoxymethyl)oxolane
2-(ethoxymethyl)tetrahydroFuran
2-Aethoxymethyl-tetrahydro-furan
tetrahydrofurfuryl ethoxylate

MDL Number

MFCD00086162

Customs Code

2932190090

FAQ

What are the physical and chemical properties of 2-(Ethoxymethyl)tetrahydrofuran (CAS: 62435-71-6)?

2-(Ethoxymethyl)tetrahydrofuran (CAS: 62435-71-6) is a colorless liquid with a distinctive odor. Its molecular weight is approximately 118.16 g/mol. It is moderately soluble in water but miscible with common organic solvents. This compound is reactive towards acids and bases, making it prone to hydrolysis under certain conditions. It exhibits good reactivity in nucleophilic substitution reactions and can act as a good solvent for various organic compounds.

How is 2-(Ethoxymethyl)tetrahydrofuran (CAS: 62435-71-6) typically synthesized?

2-(Ethoxymethyl)tetrahydrofuran (CAS: 62435-71-6) is typically synthesized via the reaction of tetrahydrofuran with ethyl bromide in the presence of an appropriate base, such as potassium tert-butoxide. The reaction proceeds via a nucleophilic substitution mechanism, yielding a high yield of the target compound. Catalysts like titanium(IV) isopropoxide can also be used to improve selectivity and reaction rates.

What industries use 2-(Ethoxymethyl)tetrahydrofuran (CAS: 62435-71-6)?

2-(Ethoxymethyl)tetrahydrofuran (CAS: 62435-71-6) is used in various industries such as pharmaceuticals, where it serves as a solvent for drug formulation and as a protective group in synthetic chemistry. It is also utilized in the production of polymers, where its unique properties enhance the performance of polymer matrices. Additionally, it finds application in sensor technology and semiconductor manufacturing due to its excellent solvating and reactive capabilities.

What precautions should be taken when handling 2-(Ethoxymethyl)tetrahydrofuran (CAS: 62435-71-6)?

When handling 2-(Ethoxymethyl)tetrahydrofuran (CAS: 62435-71-6), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Ensure the use of a fume hood to minimize inhalation of the compound. Spills should be handled with caution, using absorbent materials, and the area should be well-ventilated. Always refer to the safety data sheet (SDS) for detailed emergency response procedures and storage recommendations.