3-(Dimethylamino)-1,2-propanediol

Basic Information

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CAS Number

623-57-4

Molecular Formula

C5H13NO2

Molecular Weight

119.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

No data available

Boiling Point

217°C

Density

1.004 g/mL at 25 °C

Refractive Index

n20/D 1.4609(lit.)

SMILES

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CN(C)CC(CO)O

InChI

InChI=1S/C5H13NO2/c1-6(2)3-5(8)4-7/h5,7-8H,3-4H2,1-2H3

InChIKey

QCMHUGYTOGXZIW-UHFFFAOYSA-N

LogP

-1.0987999999999998

Topological Polar Surface Area

43.7 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

56.4

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Stability

Stable. Incompatible with oxidizing agents, acids.

Synonyms & References

English

3-Dimethylamino-1,2-propanediol
AKOS015919981
(+/-)-3-(dimethylamino)-1,2-propanediol
METHICOL
623-57-4
MFCD11111913
SY344198
BDBM50470806
SCHEMBL11137
AS-14494
EINECS 210-802-4
BP-30058
054QW4ZAMU
NSC-8655
MFCD00004714
NSC 8655
Q-200330
N,N-dimethyl-3-aminopropane-1,2-diol
Racemic 1-dimethylamino-2,3-propanediol
3-Dimethylaminopropane-1,2-diol;
3-(dimethylamino)propane-1,2-diol
(R)-3-Dimethylamino-1,2-propanediol
CS-W016584
O10883
D2072
Q27236078
BP-31241
CHEMBL26920
NSC8655
NS00043825
3-Dimethylaminopropane-1,2-diol

MDL Number

MFCD00004714

Customs Code

2922199090

FAQ

What are the physical and chemical properties of 3-(Dimethylamino)-1,2-propanediol (CAS: 623-57-4)?

3-(Dimethylamino)-1,2-propanediol (CAS: 623-57-4) is a colorless, viscous liquid with a molecular weight of approximately 130.24 g/mol. It has a high solubility in water and organic solvents. Chemically, it reacts readily with acids to form N,N-dimethylaminopropyl ethers. It is known for its stability under normal conditions but should be stored in a cool, dry place away from strong oxidizing agents.

How is 3-(Dimethylamino)-1,2-propanediol (CAS: 623-57-4) typically synthesized?

3-(Dimethylamino)-1,2-propanediol is typically synthesized by the reduction of 3-chloro-1,2-propanediol using sodium borohydride as the reducing agent. The reaction proceeds under mild conditions, and the product is isolated using standard techniques. The process is known for its high yield and selectivity, making it a preferred method in industrial applications.

What industries use 3-(Dimethylamino)-1,2-propanediol (CAS: 623-57-4)?

3-(Dimethylamino)-1,2-propanediol (CAS: 623-57-4) is widely used in pharmaceuticals for the synthesis of drug intermediates, in polymers as a monomer, and in sensors for its ability to bind to various analytes. Its use in semiconductors is also notable due to its high purity and stability, making it a valuable reagent in these industries.

What precautions should be taken when handling 3-(Dimethylamino)-1,2-propanediol (CAS: 623-57-4)?

When handling 3-(Dimethylamino)-1,2-propanediol (CAS: 623-57-4), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety glasses, and to work in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using an appropriate absorbent material. Always consult the Safety Data Sheet (SDS) for detailed information on safe handling and disposal.