2-Methylalanine (2-Aminoisobutyric Acid)

Basic Information

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CAS Number

62-57-7

Molecular Formula

C4H9NO2

Molecular Weight

103.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

≥300 °C

Boiling Point

193.35°C (rough estimate)

Density

1.1602 (rough estimate)

Flash Point

77.4℃

Solubility

SOLUBLE

Refractive Index

1.4183 (estimate)

SMILES

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CC(C)(C(=O)O)N

InChI

InChI=1S/C4H9NO2/c1-4(2,5)3(6)7/h5H2,1-2H3,(H,6,7)

InChIKey

FUOOLUPWFVMBKG-UHFFFAOYSA-N

LogP

-0.163 (est)

pKa

2.36(at 25℃)

Topological Polar Surface Area

63.31999999999999 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

87.7

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

AM20100517
Propanoic acid, 2-amino-2-methyl-
ALPHA-AMINOISOBUTYRIC ACID
NSC-16590;2-Methylalanine;H-Aib-OH
.ALPHA.-AMINOISOBUTYRIC ACID [MI]
SCHEMBL23312
2-amino-isobutyric acid
Aminoisobutyric acid
2-Methylalanine
2-Aminoisobutyric acid, 98%
a,a-Dimethylglycine
A-6036
AS-15790
a-Methylalanine
HY-Y0124
BP-12097
.alpha.-Methylalanine
FT-0611252
857402-27-8
F8889-8339
2-Aminoisobutyric acid
2-amino-2-methyl-propanoic acid
a-Aminoisobutyric acid
alpha-Aminoisobutyrate
DTXSID0058772
CS-B0930
65503-84-6
FT-0671434
MFCD00008049
a-Aminoisobutanoic acid
alpha-Aminoisobutanoic acid

MDL Number

MFCD00008049

Customs Code

29224995

FAQ

What is 2-Methylalanine (CAS: 62-57-7)?

2-Methylalanine, also known as 2-Aminoisobutyric Acid (AIB), is a non-proteinogenic amino acid with the chemical formula C4H9NO2. It features a branched hydrocarbon side chain and is commonly used in chemical research and pharmaceutical applications. As a derivative of alanine, it exhibits unique structural properties that make it valuable in synthetic chemistry and biochemistry studies.

What are the main uses of 2-Methylalanine (CAS: 62-57-7)?

2-Methylalanine (CAS: 62-57-7) is primarily used in pharmaceuticals as a building block for drug development, particularly in antiviral and anticancer therapies. It also serves as a chelating agent in industrial processes and a flavor enhancer in food science. In research, it is employed to study amino acid metabolism and as a precursor for peptide synthesis and organic compounds.

Is 2-Methylalanine (CAS: 62-57-7) safe?

2-Methylalanine (CAS: 62-57-7) is generally considered safe when handled properly in controlled environments. It has low toxicity but may cause mild skin or eye irritation upon direct contact. Safety standards recommend using protective gloves, goggles, and ensuring adequate ventilation during handling. Adherence to OSHA guidelines is advised for industrial exposure.

How should 2-Methylalanine (CAS: 62-57-7) be stored?

2-Methylalanine (CAS: 62-57-7) should be stored in a cool, dry place at 2-8°C, away from moisture and light. Use airtight containers to maintain purity and prevent degradation. Ensure storage in a well-ventilated area to avoid inhalation risks. Proper labeling and secure containment are essential for long-term stability and safety.