Benzocaine EP Impurity E | CAS No. 62-23-7

Q: What is Benzocaine EP Impurity E (CAS: 62-23-7)?

Benzocaine EP Impurity E, with the CAS number 62-23-7, is a chemical compound identified as an impurity in the pharmaceutical product Benzocaine. It is an ester derivative of p-aminobenzoic acid and is commonly found in topical anesthetic formulations. This compound is known for its low solubility in water and its ability to act as a local anesthetic in small quantities, though it is primarily of interest as a contaminant in drug manufacturing processes.

Q: What are the main uses of Benzocaine EP Impurity E (CAS: 62-23-7)?

Benzocaine EP Impurity E (CAS: 62-23-7) is primarily used in the pharmaceutical industry as an impurity in the synthesis of Benzocaine. It may also appear in related research contexts for quality control and analytical testing. Due to its chemical similarity to Benzocaine, it is important to identify and monitor this impurity to ensure the safety and efficacy of final drug products.

Q: Is Benzocaine EP Impurity E (CAS: 62-23-7) safe?

Benzocaine EP Impurity E (CAS: 62-23-7) is generally considered safe when present in trace amounts in pharmaceutical products, as it is not intended for therapeutic use. However, proper handling and storage are necessary to prevent contamination. Safety standards for this compound are typically guided by pharmaceutical regulations and purity requirements during drug production and testing.

Q: How should Benzocaine EP Impurity E (CAS: 62-23-7) be stored?

Benzocaine EP Impurity E (CAS: 62-23-7) should be stored in a cool, dry, and dark place to maintain its stability. It is recommended to keep it in a sealed container away from moisture and light exposure. Proper storage conditions help prevent degradation and ensure its integrity during analytical testing and quality control procedures.

Benzocaine EP Impurity E

Basic Information

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CAS Number

62-23-7

Molecular Formula

C7H5NO4

Molecular Weight

167.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

237-240 °C

Boiling Point

359.1°C at 760 mmHg

Density

1.61

Water Solubility

<0.1 g/100 mL at 26 ºC

Solubility

0.42g/l

Refractive Index

1.6280 (estimate)

SMILES

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C1=CC(=CC=C1C(=O)O)[N+](=O)[O-]

InChI

InChI=1S/C7H5NO4/c9-7(10)5-1-3-6(4-2-5)8(11)12/h1-4H,(H,9,10)

InChIKey

OTLNPYWUJOZPPA-UHFFFAOYSA-N

LogP

log Kow = 1.89

pKa

3.41(at 25℃)

Complexity

190

Safety Information

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GHS Hazard Pictograms

H302

H318

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H318 Causes serious eye damage
Serious eye damage/eye irritation

Stability

Stable. Combustible. Incompatible with strong oxidizing agents, cyanides, strong bases.

Sensitiveness

对湿度敏感

Synonyms & References

English

4-Nitrobenzoicacid
AC-10993
4-Nitrobenzenecarboxylic acid
CS-W020075
p-nitro-benzoicacid
Nitrodracylic acid
NCGC00091607-01
AI3-00149
Benzoic acid, 4-nitro-
PNBA
4-NITROBENZOIC-2,6-D2 ACID
C18625
p-nitro benzoic acid
4-nitrobenzoesyre
DTXSID3020966
AKOS024268501
SCHEMBL43476
4-NITROBENZOIC ACID [USP-RS]
DTXCID90966
4-AMINOBENZOIC ACID IMPURITY A [EP IMPURITY]
D70606
AE-562/40227261
InChI=1/C7H5NO4/c9-7(10)5-1-3-6(4-2-5)8(11)12/h1-4H,(H,9,10
MLS002454442
SY002161
Z57127484
Tox21_201258
CAS-62-23-7
1-Carboxy-4-nitrobenzene
PD033171
CCRIS 1185

MDL Number

MFCD00007352

Customs Code

29163900

FAQ

What is Benzocaine EP Impurity E (CAS: 62-23-7)?

Benzocaine EP Impurity E, with the CAS number 62-23-7, is a chemical compound identified as an impurity in the pharmaceutical product Benzocaine. It is an ester derivative of p-aminobenzoic acid and is commonly found in topical anesthetic formulations. This compound is known for its low solubility in water and its ability to act as a local anesthetic in small quantities, though it is primarily of interest as a contaminant in drug manufacturing processes.

What are the main uses of Benzocaine EP Impurity E (CAS: 62-23-7)?

Benzocaine EP Impurity E (CAS: 62-23-7) is primarily used in the pharmaceutical industry as an impurity in the synthesis of Benzocaine. It may also appear in related research contexts for quality control and analytical testing. Due to its chemical similarity to Benzocaine, it is important to identify and monitor this impurity to ensure the safety and efficacy of final drug products.

Is Benzocaine EP Impurity E (CAS: 62-23-7) safe?

Benzocaine EP Impurity E (CAS: 62-23-7) is generally considered safe when present in trace amounts in pharmaceutical products, as it is not intended for therapeutic use. However, proper handling and storage are necessary to prevent contamination. Safety standards for this compound are typically guided by pharmaceutical regulations and purity requirements during drug production and testing.

How should Benzocaine EP Impurity E (CAS: 62-23-7) be stored?

Benzocaine EP Impurity E (CAS: 62-23-7) should be stored in a cool, dry, and dark place to maintain its stability. It is recommended to keep it in a sealed container away from moisture and light exposure. Proper storage conditions help prevent degradation and ensure its integrity during analytical testing and quality control procedures.