3-Ethoxyacryloyl Chloride

Basic Information

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CAS Number

6191-99-7

Molecular Formula

C5H7ClO2

Molecular Weight

134.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

75°C/10mmHg

Density

1.125

Refractive Index

1.4860 to 1.4910

SMILES

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CCOC=CC(=O)Cl

InChI

InChI=1S/C5H7ClO2/c1-2-8-4-3-5(6)7/h3-4H,2H2,1H3

InChIKey

SFMFACMIOWQIPR-UHFFFAOYSA-N

LogP

1.302

Topological Polar Surface Area

26.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

98.6

Safety Information

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Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H290 May be corrosive to metals
Corrosive to Metals

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8/3 Class 8/3

Synonyms & References

English

EK7NKC6WE4
InChI=1/C5H7ClO2/c1-2-8-4-3-5(6)7/h3-4H,2H2,1H3/b4-3
(2E)-3-ethoxyprop-2-enoyl chloride
(2e)-3-(ethyloxy)-2-propenoyl chloride
6191-99-7
EN300-107948
99471-66-6
(E)-3-ethoxy-acrylic acid chloride
(E)-3-ethoxy-acryloyl chloride
3-Ethoxyacryloyl chloride
3-Ethoxy-acryloyl chloride, >=85% (H-NMR)
beta-ethoxyacrylic acid chloride
Trans-3-Ethoxypropenoyl chloride
(e)-3-ethoxy-2-propenoyl chloride
GS-6347
NS00044714
3-Ethoxy-acryloyl chloride
3-ethoxyprop-2-enoyl chloride
Acryloyl chloride, 3-ethoxy-
2-Propenoyl chloride, 3-ethoxy-
SCHEMBL94661
trans-3-ethoxyacryloyl chloride
AKOS015838849
EINECS 228-239-8
(E)-3-ETHOXYACRYLOYL CHLORIDE
(2E)-3-ethoxy-2-propenoyl chloride
2-Propenoyl chloride, 3-ethoxy-, (2E)-
AMY22514
SFMFACMIOWQIPR-ONEGZZNKSA-N
MFCD09029675
(E)-3-ethoxyprop-2-enoyl chloride

MDL Number

MFCD09029675

Customs Code

2918990090

FAQ

What are the physical and chemical properties of 3-Ethoxyacryloyl Chloride (CAS: 6191-99-7)?

3-Ethoxyacryloyl Chloride (CAS: 6191-99-7) is a colorless liquid with a strong pungent odor. It has a molecular weight of 144.07 g/mol and a boiling point of 50-55°C. It is soluble in water and organic solvents. This compound is highly reactive, particularly towards nucleophiles and hydrolysis, making it useful in polymer synthesis and pharmaceutical applications.

How is 3-Ethoxyacryloyl Chloride (CAS: 6191-99-7) typically synthesized?

3-Ethoxyacryloyl Chloride is typically synthesized by the chlorination of 3-ethoxyacrylic acid. The reaction is performed under anhydrous conditions using a catalytic amount of a Lewis acid such as aluminum chloride. The process yields 3-Ethoxyacryloyl Chloride in good to excellent purity and selectivity, making it a key intermediate in various chemical syntheses.

What industries use 3-Ethoxyacryloyl Chloride (CAS: 6191-99-7)?

3-Ethoxyacryloyl Chloride (CAS: 6191-99-7) finds applications in the pharmaceutical industry as a precursor for bioactive molecules, in polymer synthesis for special coatings, and in the production of sensors and semiconductors due to its reactivity and functional groups.

What precautions should be taken when handling 3-Ethoxyacryloyl Chloride (CAS: 6191-99-7)?

When handling 3-Ethoxyacryloyl Chloride (CAS: 6191-99-7), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation exposure. Ensure proper storage in a cool, dry place away from sources of heat and moisture. In case of spills, neutralize with a base and collect the material for disposal according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.