Benzoyl bromide

Basic Information

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CAS Number

618-32-6

Molecular Formula

C7H5BrO

Molecular Weight

185.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

-24 °C

Boiling Point

219°C

Density

1.57 g/mL at 25 °C

Refractive Index

n20/D 1.589(lit.)

SMILES

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BrC(=O)c1ccccc1

InChI

InChI=1S/C7H5BrO/c8-7(9)6-4-2-1-3-5-6/h1-5H

InChIKey

AQIHMSVIAGNIDM-UHFFFAOYSA-N

LogP

2.2217000000000002

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

106

Safety Information

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Hazard Statement

H227 Combustible liquid
Flammable liquids

H290 May be corrosive to metals
Corrosive to Metals

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

对光和湿度敏感

Synonyms & References

English

Benzoyl bromide
benzoylbromid
Benzoyl bromide, 97%
AQIHMSVIAGNIDM-UHFFFAOYSA-N
BENZOYLBROMIDE
BzBr
benzoic acid bromide
9276AB
Benzoic acid bromide;Benzenecarbonyl bromide
TL8003954
ST24030110
B0104
A23238
InChI=1/C7H5BrO/c8-7(9)6-4-2-1-3-5-6/
benzoyl bromide

MDL Number

MFCD00000112

Customs Code

2916399090

FAQ

What are the physical and chemical properties of benzoyl bromide (CAS: 618-32-6)?

Benzoyl bromide (CAS: 618-32-6) is a crystalline solid with a molecular weight of approximately 210.02 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and dichloromethane. Chemically, it is highly reactive, particularly towards nucleophiles and bases, making it useful in organic synthesis. It is also known for its ability to undergo electrophilic aromatic substitution reactions.

How is benzoyl bromide (CAS: 618-32-6) typically synthesized?

Benzoyl bromide (CAS: 618-32-6) is typically synthesized via a reaction between benzoyl chloride and bromine in the presence of a catalyst such as iron(III) bromide. The reaction is typically conducted under anhydrous conditions to prevent side reactions. The yield is generally high, and the product is purified by recrystallization from an appropriate solvent.

What industries use benzoyl bromide (CAS: 618-32-6)?

Benzoyl bromide (CAS: 618-32-6) is used in various industries due to its chemical properties. It is widely used in pharmaceuticals for synthesizing various compounds, in polymers for modifying properties, in sensors for detection mechanisms, and in semiconductors for doping processes. Additionally, it finds applications in organic synthesis and as a reagent in analytical chemistry.

What precautions should be taken when handling benzoyl bromide (CAS: 618-32-6)?

When handling benzoyl bromide (CAS: 618-32-6), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be handled carefully and neutralized with an appropriate solvent. Always consult the Safety Data Sheet (SDS) for detailed instructions and emergency procedures.