Ethyl nicotinate

Basic Information

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CAS Number

614-18-6

Molecular Formula

C8H9NO2

Molecular Weight

151.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

8-10 °C

Boiling Point

223-224 °C

Density

1.107 g/mL at 25 °C

Water Solubility

miscible

Solubility

50g/l

Refractive Index

n20/D 1.504(lit.)

SMILES

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CCOC(=O)c1cccnc1

InChI

InChI=1S/C8H9NO2/c1-2-11-8(10)7-4-3-5-9-6-7/h3-6H,2H2,1H3

InChIKey

XBLVHTDFJBKJLG-UHFFFAOYSA-N

LogP

1.2583

Topological Polar Surface Area

39.19 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

136

Safety Information

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GHS Hazard Pictograms

H315

H318

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

对空气和光线敏感

Synonyms & References

English

Ethyl nicotinate
3-PYRIDINECARBOXYLIC ACID ETHYL ESTER
ETHYL 3-PYRIDINECARBOXYLATE
ethyl nicotinoate
ETHYL PYRIDINE-3-CARBOXYLATE
NICOTINIC ACID ETHYL ESTER
RARECHEM AL BI 0185
3-(Ethoxycarbonyl)pyridine
3-Carbethoxypyridine
Apamid
Ba 2673
beta-Pyridinecarboxylic acid ethyl ester
Ignicut
Ignocut
Mucotherm
Nicaethan
Nikethan
Nikithan
pyridine-3-carboxylicacidethylester
3-Picolinic acid ethyl ester
nicotinic ethyl ester
3-Pyridinecarboxylic acid, ethyl ester
Ethylnicotinate
Nicotinic acid, ethyl ester
NIJ3H353YH
XBLVHTDFJBKJLG-UHFFFAOYSA-N
.beta.-
Ethyl 3-Pyridinecarboxylate
Nicotinic Acid Ethyl Ester
3-Pyridinecarboxylic Acid Ethyl Ester
Ethyl 3-pyridinecarboxylate

MDL Number

MFCD00006389

Customs Code

29333999

FAQ

What is Ethyl nicotinate (CAS: 614-18-6)?

Ethyl nicotinate is a chemical compound with the formula C8H11NO2. It is an ester of nicotinic acid and ethanol, commonly used as a precursor in pharmaceutical and industrial applications. This compound is a white crystalline solid, slightly soluble in water, and has a characteristic odor. It is known for its role in metabolic studies and as a component in certain drug formulations.

What are the main uses of Ethyl nicotinate (CAS: 614-18-6)?

Ethyl nicotinate is primarily used in pharmaceuticals as a prodrug for nicotinic acid, aiding in the treatment of hyperlipidemia. It also serves as a fragrance and flavoring agent in the food industry, and is utilized in research for studying vitamin B3 metabolism. Additionally, it finds applications in the synthesis of other nicotinic acid derivatives and as a stabilizer in some chemical processes.

Is Ethyl nicotinate (CAS: 614-18-6) safe?

Ethyl nicotinate is generally considered safe when used in accordance with safety guidelines. However, it may cause mild skin irritation or respiratory discomfort with prolonged exposure. Safety standards recommend handling in a well-ventilated area and using protective gloves. It is approved for use in food and pharmaceuticals by regulatory bodies like the FDA, but proper precautions are essential during storage and application.

How should Ethyl nicotinate (CAS: 614-18-6) be stored?

Ethyl nicotinate should be stored in a cool, dry place, away from direct light, in sealed, airtight containers. Maintain storage temperature below 25°C and humidity levels below 60% to ensure stability. Keep it in a well-ventilated area and avoid contact with incompatible substances. Proper storage prevents degradation and maintains its chemical integrity for extended periods.