Triprolidine hydrochloride monohydrate

Basic Information

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CAS Number

6138-79-0

Molecular Formula

C19H22N2.ClH.H2O

Molecular Weight

332.88 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

115-120 ºC

Boiling Point

462 ºC at 760 mmHg

Density

1.061

Water Solubility

>=10 g/100 mL at 20 ºC

Flash Point

233.2 ºC

Solubility

alcohol: soluble1 in 1.5 of solvent

SMILES

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CC1=CC=C(C=C1)C(=CCN2CCCC2)C3=CC=CC=N3.O.Cl

InChI

InChI=1S/C19H22N2.ClH.H2O/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;;/h2-3,6-12H,4-5,13-15H2,1H3;1H;1H2/b18-11+;;

InChIKey

CUZMOIXUFHOLLN-UMVVUDSKSA-N

LogP

3.5146200000000016

Topological Polar Surface Area

47.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

336

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Stability

Stable, but discolours in light. Incompatible with strong oxidizing agents.

Synonyms & References

English

CS-0013069
TRIPROLIDINE HYDROCHLORIDE MONOHYDRATE [MART.]
NSC-757361
Venen (TN)
TRIPROLIDINE HYDROCHLORIDE [USP MONOGRAPH]
CORPHED COMPONENT TRIPROLIDINE HYDROCHLORIDE
TRIPHED COMPONENT TRIPROLIDINE HYDROCHLORIDE
BS-17733
EN300-1692895
TRILITRON COMPONENT TRIPROLIDINE HYDROCHLORIDE
TRIPROLIDINE HYDROCHLORIDE MONOHYDRATE [MI]
Actidilon
(E)-2-(3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)pyridine monohydrochloride monohydrate
s5447
Pro-Entra
Pyridine, 2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, monohydrochloride, monohydrate, (E)-
SCHEMBL1140974
Q27114841
TRIPROLIDINE HYDROCHLORIDE COMPONENT OF MYFED
TRIACIN-C COMPONENT TRIPROLIDINE HYDROCHLORIDE
TRIPROLIDINE HYDROCHLORIDE MONOHYDROCHLORIDE MONOHYDRATE
TRIPROLIDINE HYDROCHLORIDE COMPONENT OF HISTAFED
D01782
D70442
trans-TriprolidineHydrochloride
ACTAHIST COMPONENT TRIPROLIDINE HYDROCHLORIDE
HISTAFED COMPONENT TRIPROLIDINE HYDROCHLORIDE
Pyridine, 2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, monohydrochloride, monohydrate; Pyridine, 2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, monohydrochloride, monohydrate, (E)-; Pyridine, 2-[3-(1-pyrrolidinyl)-1-p-tolylpropenyl]-, monohydrochloride, monohydrate, stereoisomer; Triprolidine hydrochloride monohydrate
CCRIS 7215
ALLERFED COMPONENT TRIPROLIDINE HYDROCHLORIDE
DTXSID0021410

MDL Number

MFCD00150574

FAQ

What is Triprolidine hydrochloride monohydrate (CAS: 6138-79-0)?

Triprolidine hydrochloride monohydrate is a derivative of triprolidine, a sedating antihistamine. It has the chemical formula C18H23ClN2·HCl·H2O and is used in pharmaceuticals for treating allergies and hay fever symptoms.

What are the main uses of Triprolidine hydrochloride monohydrate (CAS: 6138-79-0)?

Triprolidine hydrochloride monohydrate is primarily used in the pharmaceutical industry as an antihistamine for treating allergic reactions and symptoms such as sneezing, itching, and runny nose. It is also used in conjunction with other medications in combination products.

Is Triprolidine hydrochloride monohydrate (CAS: 6138-79-0) safe?

Triprolidine hydrochloride monohydrate is generally considered safe when used as directed. However, it can cause drowsiness and other side effects. Users should follow dosing instructions and consult a healthcare provider for safe use.

How should Triprolidine hydrochloride monohydrate (CAS: 6138-79-0) be stored?

Triprolidine hydrochloride monohydrate should be stored in a tightly sealed container at room temperature, away from direct heat and light. The container should be kept in a cool, dry place, and out of reach of children and pets.