4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinol | CAS No. 612501-52-7

4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinol

Basic Information

CAS Number

612501-52-7

Molecular Formula

C15H11ClFN3O2

Molecular Weight

319.72 g/mol

AD

Basic Physical Properties

OC1=CC2=C(NC3=CC=CC(Cl)=C3F)N=CN=C2C=C1OC

InChI

InChI=1S/C15H11ClFN3O2/c1-22-13-6-11-8(5-12(13)21)15(19-7-18-11)20-10-4-2-3-9(16)14(10)17/h2-7,21H,1H3,(H,18,19,20)

InChIKey

VZBZUFGPXJGXNJ-UHFFFAOYSA-N

LogP

3.8801000000000014

Topological Polar Surface Area

67.27 Ų

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

379

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • 4-(3-chloro-2-fluoroanilino)-6-hydroxy-7-methoxyquinazoline
  • 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ol
  • 4-(3-Chloro-2-fluoroanilino)-6-hydroxy-7- methoxyquinazoline
  • 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-ol
  • VZBZUFGPXJGXNJ-UHFFFAOYSA-N
  • AK549879
  • 4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-ol
  • 4-(3-chloro-2-fluoroanilino)-7-methoxy-6-hydroxyquinazoline
  • 4-[(3-chloro-2-fluor

MDL Number

MFCD26394834

FAQ

What is 4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinol (CAS: 612501-52-7)?

4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinol is a quinazoline derivative with the CAS number 612501-52-7. It is a white crystalline solid with a molecular formula of C15H10ClFN2O. This compound has a pungent odor and exhibits potential pharmacological activities.

What are the main uses of 4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinol (CAS: 612501-52-7)?

4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinol is primarily used in the pharmaceutical industry as an intermediate for the development of new drugs. It also shows promise in cancer research and as a potential therapeutic agent. Its use in other industries is limited due to its specialized nature.

Is 4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinol (CAS: 612501-52-7) safe?

4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinol is generally considered safe for industrial use when proper handling and safety measures are followed. However, prolonged exposure to this compound, especially in its crystalline form, may cause irritation to the skin and eyes. Protective gloves and goggles are recommended during handling. Ingestion or inhalation should be strictly avoided.

How should 4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinol (CAS: 612501-52-7) be stored?

4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinol should be stored in a cool, dry place, away from direct sunlight and heat sources. The storage temperature should not exceed 25°C. Ensure the container is tightly sealed to prevent moisture absorption. Suitable containers include amber glass bottles to protect from light exposure. It is essential to keep the compound away from incompatible materials such as strong oxidizers and acids.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...