trimethylsilylethynylmagnesium bromide | CAS No. 61210-52-4

trimethylsilylethynylmagnesium bromide

Basic Information

CAS Number

61210-52-4

Molecular Formula

C5H9BrMgSi

Molecular Weight

88.23 g/mol

AD

Basic Physical Properties

C[Si](C)(C)C#[C-].[Mg+2].[Br-]

InChI

InChI=1S/C4H12Si/c1-5(2,3)4/h1-4H3

InChIKey

CZDYPVPMEAXLPK-UHFFFAOYSA-N

LogP

1.9544

Topological Polar Surface Area

0.0 Ų

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

77.8

Synonyms & References

English

  • 61210-52-4
  • trimethylsilylethynylmagnesium bromide
  • Magnesium, bromo[(trimethylsilyl)ethynyl]-
  • DTXSID50446055
  • magnesium;ethynyl(trimethyl)silane;bromide
  • magnesium,ethynyl(trimethyl)silane,bromide

FAQ

What regulatory guidelines apply to trimethylsilylethynylmagnesium bromide (CAS: 61210-52-4)?

Trimethylsilylethynylmagnesium bromide (CAS: 61210-52-4) is regulated under various guidelines including the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), REACH in the EU, and FDA/EPA requirements. It is classified as a hazardous substance due to its flammability, reactivity, and toxicity. Specific handling, storage, and disposal methods must comply with local and international regulations to ensure safety and environmental protection.

Are there alternatives to trimethylsilylethynylmagnesium bromide (CAS: 61210-52-4) in synthesis?

Alternatives to trimethylsilylethynylmagnesium bromide (CAS: 61210-52-4) include other Grignard reagents or organolithium compounds. For example, tert-butyllithium, methylmagnesium chloride, and ethyllithium are common substitutes. These alternatives offer similar reactivity but may have different reaction conditions or hazards, making them suitable for specific synthetic pathways.

What is the market or research trend for trimethylsilylethynylmagnesium bromide (CAS: 61210-52-4)?

The market for trimethylsilylethynylmagnesium bromide (CAS: 61210-52-4) is driven by its use in organic synthesis, particularly in the preparation of alkynes and functionalized compounds. Research trends include exploring its use in sustainable chemistry and developing safer, more eco-friendly alternatives. The demand is influenced by the pharmaceutical and materials science industries, but concerns over its toxicity and reactivity continue to drive the search for safer alternatives.

How should waste containing trimethylsilylethynylmagnesium bromide (CAS: 61210-52-4) be handled?

Waste containing trimethylsilylethynylmagnesium bromide (CAS: 61210-52-4) should be collected in appropriate, labeled containers and stored in a well-ventilated area away from heat sources. For disposal, consult local regulations and professional waste management services. Incineration is an effective method, but ensure it is conducted in a controlled manner to prevent emission of harmful compounds. Environmental protection measures include minimizing exposure and proper documentation of waste disposal procedures.

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