N-Formyl-L-leucine

Basic Information

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CAS Number

6113-61-7

Molecular Formula

C7H13NO3

Molecular Weight

159.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Physical Properties

Melting Point

141.0 to 144.0 deg-C

Boiling Point

284.67°C (rough estimate)

Density

1.2013 (rough estimate)

Flash Point

171.9 °C

Refractive Index

-39.5 ° (C=1, H2O)

SMILES

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CC(C)CC(C(=O)O)NC=O

InChI

InChI=1S/C7H13NO3/c1-5(2)3-6(7(10)11)8-4-9/h4-6H,3H2,1-2H3,(H,8,9)(H,10,11)/t6-/m0/s1

InChIKey

HFBHOAHFRNLZGN-LURJTMIESA-N

LogP

0.2316999999999998

Topological Polar Surface Area

66.4 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

145

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

NSC-334321
N-formyl L leucine
N-Formyl-L-leucine
N-Formylleucine #
L-Leucine, N-formyl-
AKOS010389171
N-Formyl-L-leucine (For-L-Leu-OH)
F0131
DTXSID90878997
(2S)-2-formamido-4-methylpentanoic acid
EINECS 228-080-4
For-Leu-OH
N-formyl l-leu
n-formyl-s-leucine
N-Formyl-S-leucine;N-Formylleucine;NSC 334321
MFCD00055861
SCHEMBL1399853
formyl-l-leucine
formylleucine
CS-0009546
AKOS005255679
Formylleucin
I11527
DS-9758
NS00045497
N-formyl-(S)-leucine
FORMYLLEUCINE [USP IMPURITY]
HY-I0591
N-Formyl-Leu-OH
6113-61-7
5THA63Y4FF

MDL Number

MFCD00055861

Customs Code

2924199090

FAQ

What are the physical and chemical properties of N-Formyl-L-leucine (CAS: 6113-61-7)?

N-Formyl-L-leucine (CAS: 6113-61-7) is a crystalline compound with a molecular weight of approximately 170.23 g/mol. It is slightly soluble in water and other polar solvents. The compound is thermally stable but can react with reducing agents. It is used in various biochemical and pharmaceutical applications due to its reactivity and structural properties.

How is N-Formyl-L-leucine (CAS: 6113-61-7) typically synthesized?

N-Formyl-L-leucine (CAS: 6113-61-7) is synthesized by acylation of L-leucine with formic acid in the presence of a catalytic amount of a strong acid like trifluoroacetic acid (TFA). The reaction is highly selective and yields a high percentage of the desired product.

What industries use N-Formyl-L-leucine (CAS: 6113-61-7)?

N-Formyl-L-leucine (CAS: 6113-61-7) is primarily used in the pharmaceutical industry for its role as a metabolic probe and in protein chemistry. It is also utilized in biochemical research, as a building block for peptides, and in the development of certain chemical sensors.

What precautions should be taken when handling N-Formyl-L-leucine (CAS: 6113-61-7)?

When handling N-Formyl-L-leucine (CAS: 6113-61-7), it is important to use appropriate personal protective equipment (PPE) such as gloves and goggles. The compound should be stored in a cool, dry place, away from oxidizing agents. In case of a spill, it should be cleaned up using appropriate methods, and the area should be ventilated. Always refer to the safety data sheet (SDS) for detailed handling instructions.