(2R)-Hydroxy(phenyl)acetic acid

Basic Information

View in Editor

CAS Number

611-71-2

Molecular Formula

C8H8O3

Molecular Weight

152.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

131-133 °C

Boiling Point

321.8°C at 760 mmHg

Density

1.1677 (rough estimate)

Water Solubility

It is partly soluble in water, freely soluble in isopropyl and ethyl alcohol.

Solubility

109.8g/l soluble

Refractive Index

-153.5 ° (C=1, H2O)

Vapor Pressure

0.0±0.7 mmHg at 25°C

Specific Rotation

-150 º (c=2.5, H2O)

SMILES

View in Editor

O[C@@H](C(=O)O)c1ccccc1

InChI

InChI=1S/C8H8O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7,9H,(H,10,11)/t7-/m1/s1

InChIKey

IWYDHOAUDWTVEP-SSDOTTSWSA-N

LogP

0.8046

pKa

3.37(at 25℃)

Topological Polar Surface Area

57.53 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

138

Safety Information

View Safety Information

GHS Hazard Pictograms

H318

Hazard Statement

H318 Causes serious eye damage
Serious eye damage/eye irritation

Storage Conditions

2-8℃

Stability

Stable, but light sensitive. Combustible. Incompatible with strong bases, strong oxidizing agents.

Sensitiveness

Light Sensitive

Synonyms & References

English

(R)-2-Hydroxy-2-phenylacetic acid
(R)-(-)-alpha-Hydroxyphenylacetic acid
R-(-)-mandelic acid
(R)-(-)-mandelic
(R)-Hydroxyphenylaceticacid
RARECHEM AL BO 1446
(R)-(-)-2-MANDELIC ACID
(R)-(-)-AMYGDALIC ACID
(R)-ALPHA-HYDROXYPHENYLACETIC ACID
R-(-)-ALPHA-HYDROXYPHENYLACETIC ACID
D-mandelic acid
D-DL-Mandelic acid
R-(-)-DL-Mandelic acid
R-DL-Mandelic acid
D-(-)-Mandelic Acid
(D)-(-)-Mandelicacid
(R)-(-)-Mandelic Aci
(R)-(-)-Mandelic acid
DL-Mandelic acid
Mandelic acid
D mandelic acid
a-Hydroxy-benzeneacetic acid
Hydroxy(phenyl)acetic acid
2-Phenylglycolic acid
2-Hydroxy-2-phenylacetic acid
alpha-Hydroxyphenylacetic acid
(R)-alpha-Hydroxy-benzeneacetic acid
(R)-2-Phenylglycolic acid
(r)-mandelic acid
(-)-Mandelic acid
D(-)-Mandelic acid

MDL Number

MFCD00064251

Customs Code

2918199090

FAQ

What is (2R)-Hydroxy(phenyl)acetic acid (CAS: 611-71-2)?

(2R)-Hydroxy(phenyl)acetic acid, with CAS number 611-71-2, is a chiral organic compound that contains a hydroxyl group and a phenyl ring attached to an acetic acid backbone. It is a white crystalline solid with moderate solubility in water and is commonly used in the synthesis of various pharmaceutical and industrial compounds due to its functional groups and stereochemical properties.

What are the main uses of (2R)-Hydroxy(phenyl)acetic acid (CAS: 611-71-2)?

(2R)-Hydroxy(phenyl)acetic acid (CAS: 611-71-2) is primarily used in pharmaceutical research for the development of drugs targeting metabolic disorders and inflammation. It also serves as an intermediate in the production of certain agrochemicals and is employed in organic synthesis for its versatile reactivity and chiral center. Additionally, it is used in analytical chemistry for structural analysis and as a reagent in various chemical processes.

Is (2R)-Hydroxy(phenyl)acetic acid (CAS: 611-71-2) safe?

(2R)-Hydroxy(phenyl)acetic acid (CAS: 611-71-2) is generally considered safe when handled properly. However, it should be treated with care as it may cause mild irritation to the skin and eyes. Safety standards recommend using appropriate personal protective equipment (PPE) such as gloves and goggles. It is important to follow standard laboratory safety protocols to minimize exposure and ensure safe handling.

How should (2R)-Hydroxy(phenyl)acetic acid (CAS: 611-71-2) be stored?

(2R)-Hydroxy(phenyl)acetic acid (CAS: 611-71-2) should be stored in a cool, dry, and well-ventilated area away from direct sunlight. It is best kept in a sealed container to prevent moisture absorption and maintain stability. Storage conditions should be below 25°C and at low humidity to avoid degradation. Always store in a safe location away from incompatible substances.