1-(2-Hydroxyphenyl)-1-propanone

Basic Information

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CAS Number

610-99-1

Molecular Formula

C9H10O2

Molecular Weight

150.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

150°C/80mmHg

Density

1.094 g/mL at 25 °C

Refractive Index

n20/D 1.548(lit.)

SMILES

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CCC(=O)C1=CC=CC=C1O

InChI

InChI=1S/C9H10O2/c1-2-8(10)7-5-3-4-6-9(7)11/h3-6,11H,2H2,1H3

InChIKey

KDUWXMIHHIVXER-UHFFFAOYSA-N

LogP

1.9849

Topological Polar Surface Area

37.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

143

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

NS00003335
2'-hydroxy-propiophenone
EC 210-244-1
W-105197
AC8486
NSC 3785
AI311684AI3-11684
AS-12054
2-Propionylphenol
2'-Hydroxypropiophenone, 97%
o-Propiophenol
CHEMBL151116
AI3 11684
CHEBI:192968
InChI=1/C9H10O2/c1-2-8(10)7-5-3-4-6-9(7)11/h3-6,11H,2H2,1H
FT-0612634
EN300-17641
2'-Hydroxypropiophenone
SY015244
2-Hydroxyphenyl ethyl ketone
1-(2-Hydroxyphenyl)-1-propanone
AKOS000121339
EINECS 210-244-1
2?-HYDROXYPROPIOPHENONE
ortho-Hydroxypropiophenone
1-(2-Hydroxy-phenyl)-propan-1-one
NSC3785
H0298
Ethyl 2-Hydroxyphenyl Ketone
MFCD00002220
o-Hydroxypropiophenone

MDL Number

MFCD00002220

Customs Code

2914501900

FAQ

What are the physical and chemical properties of 1-(2-Hydroxyphenyl)-1-propanone (CAS: 610-99-1)?

1-(2-Hydroxyphenyl)-1-propanone (CAS: 610-99-1) is a crystalline solid with a molecular weight of approximately 168.17 g/mol. It has a melting point of around 62-63°C and is slightly soluble in water. The compound is known for its reactivity in forming esters and its stability in acidic conditions. It is often used in organic synthesis due to its reactivity and solubility characteristics.

How is 1-(2-Hydroxyphenyl)-1-propanone (CAS: 610-99-1) typically synthesized?

1-(2-Hydroxyphenyl)-1-propanone is commonly synthesized via the condensation of acetophenone and phenol in the presence of a strong acid catalyst such as concentrated sulfuric acid. The reaction is typically carried out under reflux conditions, yielding a product with a high degree of purity. The yield and selectivity can be enhanced by using appropriate reaction conditions and purification techniques.

What industries use 1-(2-Hydroxyphenyl)-1-propanone (CAS: 610-99-1)?

1-(2-Hydroxyphenyl)-1-propanone (CAS: 610-99-1) is primarily used in the pharmaceutical and polymer industries. It serves as a precursor for the synthesis of various drugs and is also utilized in the production of polyurethane and other polymer materials. Additionally, it finds applications in the development of sensors and as a chemical intermediate in semiconductor manufacturing.

What precautions should be taken when handling 1-(2-Hydroxyphenyl)-1-propanone (CAS: 610-99-1)?

When handling 1-(2-Hydroxyphenyl)-1-propanone (CAS: 610-99-1), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Proper storage in a cool, dry place away from direct sunlight is recommended. In case of spill, immediately clean up with appropriate materials and refer to the Safety Data Sheet (SDS) for detailed instructions on handling and disposal.