2-Hydroxynicotinic acid

Basic Information

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CAS Number

609-71-2

Molecular Formula

C6H5NO3

Molecular Weight

139.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

258-261 °C

Boiling Point

436℃ at 760 mmHg

Density

1.4429 (rough estimate)

Flash Point

217.5℃

Solubility

0.1 M NaOH: 0.1 g/mL, clear

Refractive Index

1.5423 (estimate)

SMILES

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C1=CNC(=O)C(=C1)C(=O)O

InChI

InChI=1S/C6H5NO3/c8-5-4(6(9)10)2-1-3-7-5/h1-3H,(H,7,8)(H,9,10)

InChIKey

UEYQJQVBUVAELZ-UHFFFAOYSA-N

LogP

0.4853999999999999

Topological Polar Surface Area

70.42 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

239

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-OHnicH
2-oxo-1H-pyridine-3-carboxylic acid
SCHEMBL107538
NICOTINIC ACID, 1,2-DIHYDRO-2-OXO-
ES6
2-ODHPCA
Oprea1_483223
EINECS 210-198-2
1,2-Dihydro-2-oxonicotinic acid
2-Hydroxypyridine-3-carboxylic acid
1,2-Dihydro-2-oxo-3-pyridinecarboxylic acid
2-Hydroxynicotinic acid, purum, >=98.0% (T)
Q27290030
F2190-0004
2-Hydroxynicotinic acid
NS00014698
2-Oxo-1,2-dihydropyridine-3-carboxylic acid, AldrichCPR
2-Hydroxy-3-pyridinecarboxylic Acid
CS-W018547
AB7337
UEYQJQVBUVAELZ-UHFFFAOYSA-
AB01020
2-oxo-1,2-dihydro-3-pyridinecarboxylic acid
AC-3028
AM20070024
A8475
NSC-226152
2-Hydroxypyridine-3-carboxylic acid, 98%
H0795
oxopyridine-3-carboxylic acid
609-71-2

MDL Number

MFCD00010100

Customs Code

2933399090

FAQ

What is 2-Hydroxynicotinic acid (CAS: 609-71-2)?

2-Hydroxynicotinic acid (CAS: 609-71-2) is a white crystalline organic compound with the chemical formula C6H5NO3. It belongs to the nicotinic acid family, featuring a hydroxyl group (-OH) at the 2nd position of the pyridine ring. This compound is known for its solubility in water and polar organic solvents, and it exhibits acidic properties due to the carboxylic group. Its molecular structure makes it a key intermediate in pharmaceutical and chemical research applications.

What are the main uses of 2-Hydroxynicotinic acid (CAS: 609-71-2)?

2-Hydroxynicotinic acid (CAS: 609-71-2) is primarily used in pharmaceuticals as a precursor for synthesizing drugs targeting metabolic disorders. It also serves in chemical research for developing derivatives with enhanced biological activity. Industrial applications include its use as a building block for organic compounds, while in food science, it may be employed as a flavor enhancer. Its versatility supports roles in biochemistry and material science research.

Is 2-Hydroxynicotinic acid (CAS: 609-71-2) safe?

2-Hydroxynicotinic acid (CAS: 609-71-2) is generally considered safe when handled properly. It has low acute toxicity but should be treated with care to avoid skin and eye contact. Safety data sheets (SDS) recommend using gloves, goggles, and ensuring adequate ventilation. It is not classified as a hazardous substance under major regulations, but standard lab safety protocols should still be followed to minimize exposure risks.

How should 2-Hydroxynicotinic acid (CAS: 609-71-2) be stored?

2-Hydroxynicotinic acid (CAS: 609-71-2) should be stored in a cool, dry place (ideally below 25°C), away from light and moisture. Keep in a sealed, airtight container to maintain stability and prevent degradation. Store in a well-ventilated area to avoid inhalation risks. Ensure proper labeling and follow safety guidelines to maintain its chemical integrity and safety during storage.