7-(Benzyloxy)-2,4-dichloro-6-methoxyquinazoline

Basic Information

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CAS Number

60771-18-8

Molecular Formula

C16H12Cl2N2O2

Molecular Weight

335.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Boiling Point

447.6±45.0°C at 760 mmHg

SMILES

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COC1=CC2=C(Cl)N=C(Cl)N=C2C=C1OCC3=CC=CC=C3

InChI

InChI=1S/C16H12Cl2N2O2/c1-21-13-7-11-12(19-16(18)20-15(11)17)8-14(13)22-9-10-5-3-2-4-6-10/h2-8H,9H2,1H3

InChIKey

PTQCMUDKRFNQCR-UHFFFAOYSA-N

LogP

4.524200000000002

Topological Polar Surface Area

44.24000000000001 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

355

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

7-(Benzyloxy)-2,4-dichloro-6-methoxyquinazoline
2,4-dichloro-6-methoxy-7-phenylmethoxyquinazoline
Quinazoline, 2,4-dichloro-6-methoxy-7-(phenylmethoxy)-
PTQCMUDKRFNQCR-UHFFFAOYSA-N
AB71551
AK136624
AX8258192
AB0073931
7-benzyloxy-2,4-dichloro-6-methoxy-quinazoline

MDL Number

MFCD16987836

FAQ

What regulatory guidelines apply to 7-(Benzyloxy)-2,4-dichloro-6-methoxyquinazoline (CAS: 60771-18-8)?

The compound 7-(Benzyloxy)-2,4-dichloro-6-methoxyquinazoline (CAS: 60771-18-8) is subject to various regulatory guidelines. It may be classified and labeled according to the Globally Harmonized System (GHS) for hazardous chemicals. In the European Union, it falls under the REACH regulations for the Registration, Evaluation, Authorisation, and Restriction of Chemicals. Additionally, the Food and Drug Administration (FDA) and the Environmental Protection Agency (EPA) may have specific requirements regarding its use, testing, and disposal.

Are there alternatives to 7-(Benzyloxy)-2,4-dichloro-6-methoxyquinazoline (CAS: 60771-18-8) in synthesis?

There are alternative reagents and methods that can be used in the synthesis of 7-(Benzyloxy)-2,4-dichloro-6-methoxyquinazoline (CAS: 60771-18-8). For instance, 2,4-dichloro-6-methoxyquinazoline can be modified with different functional groups or alternative substituents. Additionally, other quinazoline derivatives with similar structures can serve as alternatives, depending on the specific application and desired properties.

What is the market or research trend for 7-(Benzyloxy)-2,4-dichloro-6-methoxyquinazoline (CAS: 60771-18-8)?

The market for 7-(Benzyloxy)-2,4-dichloro-6-methoxyquinazoline (CAS: 60771-18-8) is primarily driven by its use in pharmaceuticals and research. Recent trends indicate a growing interest in its application as an intermediate for drug synthesis and as a component in anti-inflammatory and anti-cancer treatments. Emerging research focuses on optimizing its synthesis and exploring its potential in novel therapeutic areas.

How should waste containing 7-(Benzyloxy)-2,4-dichloro-6-methoxyquinazoline (CAS: 60771-18-8) be handled?

Waste containing 7-(Benzyloxy)-2,4-dichloro-6-methoxyquinazoline (CAS: 60771-18-8) should be handled according to strict environmental regulations. It is recommended to collect the waste in appropriate containers and ensure proper labeling. The waste should then be disposed of through incineration or professional waste disposal services that comply with local and international environmental standards. Protective measures such as gloves and safety goggles should be worn during handling to prevent exposure and ensure safety.