1-Hydroxy-2,5-pyrrolidinedione

Basic Information

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CAS Number

6066-82-6

Molecular Formula

C4H5NO3

Molecular Weight

115.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

95-98 °C

Boiling Point

262.4°C at 760 mmHg

Density

1.4769 (rough estimate)

Flash Point

112.5℃

Refractive Index

1.4080 (estimate)

SMILES

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ON1C(=O)CCC1=O

InChI

InChI=1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2

InChIKey

NQTADLQHYWFPDB-UHFFFAOYSA-N

LogP

-0.47540000000000004

Topological Polar Surface Area

57.61 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

126

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Stability

Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, strong bases. Protect from moisture.

Sensitiveness

Hygroscopic

Synonyms & References

English

1-Hydroxypyrrolidine-2,5-dione
1-Hydroxy-2,5-pyrrolidinedione
N-Hydroxysuccinimide (HOSu)
HOSu~1-Hydroxy-2,5-pyrrolidinedione
N-Hydroxysuccinimide,(1-Hydroxy-2,5-pyrrolidine- dione)
HOSu
N-Hydroxysuccinimide
NHS
HONSU
N-HYDROXY-2,5-PYRROLIDINEDIONE
N-HYDROXYSUCCINIMDE
N-HYDROXYSUCCINIMIDE POLYMER-BOUND
1-hydroxy-5-pyrrolidinedione
1-Hydroxysuccinimide
5-Pyrrolidinedione,1-hydroxy-2
N-Hydroxysuccinimide [Coupling Reagent for Peptide]
HOSU (N-Hydroxysuccinimide)
N-Hydroxy succinimide
2,5-Pyrrolidinedione, 1-hydroxy-
Succinimide, N-hydroxy-
N-hydroxysuccinimid
N-hydroxy-succinimide
MJE3791M4T
NQTADLQHYWFPDB-UHFFFAOYSA-N
1-hydroxypyrrolidin-2,5-dion
1-hydroxy-pyrrolidine-2,5-dione
N-h
1-hydroxypyrrolidine-2,5-dione

MDL Number

MFCD00005516

Customs Code

2925190090

FAQ

What is 1-Hydroxy-2,5-pyrrolidinedione (CAS: 6066-82-6)?

1-Hydroxy-2,5-pyrrolidinedione (CAS: 6066-82-6) is a cyclic organic compound with the molecular formula C4H6O3. It features a five-membered pyrrolidinedione ring containing a hydroxyl group and two ketone functionalities. This compound is known for its stability in controlled environments and is commonly used as an intermediate in chemical synthesis. Its chemical structure makes it relevant in pharmaceutical and research applications.

What are the main uses of 1-Hydroxy-2,5-pyrrolidinedione (CAS: 6066-82-6)?

1-Hydroxy-2,5-pyrrolidinedione (CAS: 6066-82-6) is primarily utilized in pharmaceuticals for synthesizing bioactive molecules and drug intermediates. It also finds applications in industrial chemistry for polymer production and as a reagent in organic synthesis. Additionally, it is employed in research settings for developing new chemical compounds and studying reaction mechanisms. Its versatility in chemical applications makes it a key compound in various sectors.

Is 1-Hydroxy-2,5-pyrrolidinedione (CAS: 6066-82-6) safe?

1-Hydroxy-2,5-pyrrolidinedione (CAS: 6066-82-6) requires careful handling due to potential toxicity. Safety guidelines recommend wearing protective gloves, goggles, and a lab coat, and working in a well-ventilated area. It should be stored in sealed containers to prevent exposure. Always consult safety data sheets (SDS) and follow OSHA standards for proper use and disposal to ensure safety in laboratory and industrial settings.

How should 1-Hydroxy-2,5-pyrrolidinedione (CAS: 6066-82-6) be stored?

1-Hydroxy-2,5-pyrrolidinedione (CAS: 6066-82-6) should be stored in a cool, dry place, preferably refrigerated at 2-8°C, to maintain stability. It is sensitive to moisture and light, so airtight, light-resistant containers made of glass or inert material are recommended. Keep it away from incompatible substances and ensure proper ventilation to prevent degradation or contamination.