6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine

Basic Information

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CAS Number

60547-97-9

Molecular Formula

C14H19N5O2

Molecular Weight

289.34 g/mol

Basic Physical Properties

Melting Point

233-238°C

Boiling Point

527 °C at 760 mmHg

Density

1.265

Flash Point

272.5 °C

Refractive Index

1.63

SMILES

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COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCNCC3)N)OC

InChI

InChI=1S/C14H19N5O2/c1-20-11-7-9-10(8-12(11)21-2)17-14(18-13(9)15)19-5-3-16-4-6-19/h7-8,16H,3-6H2,1-2H3,(H2,15,17,18)

InChIKey

APKHJGDGWQDBGM-UHFFFAOYSA-N

LogP

0.6387999999999998

Topological Polar Surface Area

85.53 Å²

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

339

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine
CHEMBL1226
SDCCGMLS-0023979.P002
PRAZOSIN METABOLITE M1
MFCD00563872
AMINODIMETHOXYQUINAZOLINYLPIPERAZINE
4-amino-6,7-dimethoxy-2-piperazinoquinazoline
2-(1-piperazinyl)-4-amino-6,7-dimethoxy-quinazoline
4-Amino-6,7-dimethoxy-2-(1-piperazinyl)quinqzoline
4-amino-6,7-dimethyoxy-2-(1-piperazinyl)-quinazoline
2-[(2,6-DIMETHYLPHENYL)AMINO]-N,N,N-TRIMETHYL-2-OXOETHANAMINIUMCL
6,7-Dimethoxy-2-(1-piperazinyl)-4-quinazolinamine
SCHEMBL608966
2-PIPERAZINO-6,7-DIMETHOXY-4-QUINAZOLINAMINE
4-Amino-6,7-dimethoxy-2-piperazino-quinazoline
4-amino-6,7-dimethoxy-2-(1-piperazinyl) quinazoline
0EC
EN300-7353400
MLS000060939
2-piperazine-4-amino-6,7-dimethoxyquinazoline
Oprea1_697372
4-amino-6,7-dimethoxy-2-(1-piperzinyl)quinazoline
2-Padqz
DTXSID00209293
FT-0640697
2-(4-PIPERAZINYL)-4-AMINO-6,7-DIMETHOXYQUINAZOLINE
BDBM50073568
6,7-Dimethoxy-2-piperazin-1-yl-quinazolin-4-ylamine
4-amino-2-piperazin-1-yl-6,7-dimethoxy-quinazoline
AC-17537
Q27253028

MDL Number

MFCD00563872

Customs Code

2933499090

FAQ

What regulatory guidelines apply to 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine (CAS: 60547-97-9)?

6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine (CAS: 60547-97-9) must comply with various regulatory guidelines. Globally, it follows GHS (Globally Harmonized System of Classification and Labelling of Chemicals) for hazard communication. In Europe, it must adhere to REACH (Registration, Evaluation, Authorization, and Restriction of Chemicals) regulations. In the US, it is subject to FDA (Food and Drug Administration) and EPA (Environmental Protection Agency) requirements, including documentation and reporting on chemical safety and environmental impact.

Are there alternatives to 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine (CAS: 60547-97-9) in synthesis?

There are several alternatives to 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine (CAS: 60547-97-9) in synthesis. Common alternatives include analogs such as 4-aminopyridine and analogs with different piperazine rings. Isomers and other structurally similar compounds can also serve as viable alternatives. In many cases, synthetic equivalents with similar functional groups are preferred for their availability and cost-effectiveness.

What is the market or research trend for 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine (CAS: 60547-97-9)?

The market for 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine (CAS: 60547-97-9) is trending towards increased research and development, particularly in the pharmaceutical and biotechnological sectors. Recent studies have shown a growing interest in its use as a potential therapeutic agent. Market trends indicate an ongoing exploration of its properties and applications, driven by its unique chemical structure and potential medicinal value. As research advances, so does the demand for this compound in academic and commercial settings.

How should waste containing 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine (CAS: 60547-97-9) be handled?

Waste containing 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine (CAS: 60547-97-9) should be handled according to strict environmental and safety protocols. It is advisable to collect waste liquids in appropriate containers and seal them tightly. For solid waste, ensure it is packaged and labeled appropriately. Incineration is a common disposal method, but professional waste disposal services are recommended to ensure compliance with local regulations. Always follow the guidelines provided by local environmental protection agencies and adhere to all safety precautions to prevent environmental contamination and ensure worker safety.