Phloretin | CAS No. 60-82-2

Phloretin

Basic Information

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CAS Number

60-82-2

Molecular Formula

C15H14O5

Molecular Weight

274.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

~260 °C

Boiling Point

534.4°C at 760 mmHg

Density

1.1827 (rough estimate)

Flash Point

291.1 °C

Solubility

0.123 mg/mL at 16 °C

Refractive Index

1.573-1.575

SMILES

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Oc1ccc(cc1)CCC(=O)c1c(O)cc(cc1O)O

InChI

InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2

InChIKey

VGEREEWJJVICBM-UHFFFAOYSA-N

LogP

2.3245000000000013

Topological Polar Surface Area

97.99000000000001 Å²

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

312

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Storage Conditions

2-8℃

Sensitiveness

Sensitive to heat and light

Synonyms & References

English

Phloretin
2',4',6',4-TETRAHYDROXYDIHYDROCHALCONE
2',4',6'-TRIHYDROXY-3-(4-HYDROXYPHENYL)-1-PROPIOPHENONE
2',4',6'-TRIHYDROXY-3-(4-HYDROXYPHENYL)-PROPIOPHENONE
2',4',6'-TRIHYDROXY-3-P-HYDROXYPHENYLPROPIOPHENONE
2,4,6-TRIHYDROXY-BETA-(4-HYDROXYPHENYL)PROPIOPHENONE
3-[4-HYDROXYPHENYL]-1-[2,4,6-TRIHYDROXYPHENYL]-1-PROPANONE
4,2',4',6'-TETRAHYDROXYDIHYDROCHALCONE
BETA-(4-HYDROXYPHENYL)-2,4,6-TRIHYDROXY-PROPIOPHENONE
PHLORETIN (NATURAL)
3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
2,4,6-Trihydroxy-B-(4-Hydroxyphenyl)Propiophenone
β-(4-hydroxyphenyl)-2,4,6-trihydroxypropiophenone
PHLORETIN(RG)
1-Propanone, 3-(4-hydroxyphenyl)-1-(2,4,6-
Dihydronaringenin
Floretin
NSC 407292
Phloretol
RJC 02792
UNII-S5J5OE47MK
2′,4′,6′-Trihydroxy-3-(4-hydroxyphenyl)propiophenone
3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone
2',4',6'-Trihydroxy-3-(4-hydroxyphenyl)propiophenone
[ "" ]
1-Propanone, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-
beta-(p-Hydroxyphenyl)phloropropiophenone
2',4',6'-Trihydroxy-3-(p-hydroxyphenyl)propiophenone
NSC407292
S5J5OE47MK
beta-(p-Hydroxyphenyl)-2,4,6-trihydrox

MDL Number

MFCD00002288

Customs Code

2942000000

FAQ

What is Phloretin (CAS: 60-82-2)?

Phloretin is a natural flavonoid compound with the chemical formula C16H14O6. It is known for its antioxidant and anti-inflammatory properties, and is commonly found in apple peels and other plant sources. Phloretin is used in various scientific and industrial applications due to its unique chemical structure and biological activity.

What are the main uses of Phloretin (CAS: 60-82-2)?

Phloretin is primarily used in pharmaceutical research for its potential health benefits, including anti-cancer and neuroprotective effects. It also serves as a food additive and is studied for its role in improving skin health. In the cosmetic industry, it is used for its antioxidant properties to protect against UV damage and enhance skin appearance.

Is Phloretin (CAS: 60-82-2) safe?

Phloretin is generally considered safe when used in appropriate amounts. However, it is important to handle it with care, as high concentrations may cause irritation. Safety standards suggest following standard lab protocols and avoiding prolonged exposure. Always consult safety data sheets for specific handling precautions.

How should Phloretin (CAS: 60-82-2) be stored?

Phloretin should be stored in a cool, dry, and dark place to maintain its stability. It is best kept in a sealed container at a temperature below 25°C and away from moisture and light. Proper storage helps preserve its chemical properties and effectiveness for various applications.