Pyrazolo[1,5-a]pyridin-2(1H)-one

Basic Information

View in Editor

CAS Number

59942-87-9

Molecular Formula

C7H6N2O

Molecular Weight

134.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Density

1.36

SMILES

View in Editor

Oc1cc2ccccn2n1

InChI

InChI=1S/C7H6N2O/c10-7-5-6-3-1-2-4-9(6)8-7/h1-5H,(H,8,10)

InChIKey

WZCJFNVSGQSWLF-UHFFFAOYSA-N

LogP

1.0398999999999996

Topological Polar Surface Area

37.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

263

Synonyms & References

English

Pyrazolo[1,5-a]pyridin-2(1H)-one
1H-pyrazolo[1,5-a]pyridin-2-one
2-HYDROXYPYRAZOLO[1,5-A]PYRIDINE
Pyrazolo[1,5-a]pyridin-2-o
pyrazolo[1,5-a]pyridin-2-ol
Pyrazolo[1,5-apyridin-2-ol
WZCJFNVSGQSWLF-UHFFFAOYSA-N
8937AB
FCH875176
1H,2H-pyrazolo[1,5-a]pyridin-2-one
BC638899
AB0081457
ST24049053
Y1674

MDL Number

MFCD19441798

Customs Code

2933990090

FAQ

What are the physical and chemical properties of Pyrazolo[1,5-a]pyridin-2(1H)-one (CAS: 59942-87-9)?

Pyrazolo[1,5-a]pyridin-2(1H)-one is a crystalline solid with a molecular weight of 176.14 g/mol. It has a high solubility in organic solvents like DMSO and ethanol. It is moderately reactive towards nucleophiles and electrophiles. The compound exhibits good thermal stability up to 200°C.

How is Pyrazolo[1,5-a]pyridin-2(1H)-one (CAS: 59942-87-9) typically synthesized?

Pyrazolo[1,5-a]pyridin-2(1H)-one is commonly synthesized via a multi-step reaction starting from pyridine and pyrazole. The process involves condensation followed by ring closure, using catalysts like palladium(II) acetate for high selectivity and yield. The overall procedure requires careful temperature control and solvent selection.

What industries use Pyrazolo[1,5-a]pyridin-2(1H)-one (CAS: 59942-87-9)?

Pyrazolo[1,5-a]pyridin-2(1H)-one is used in the pharmaceutical industry for developing potential drug candidates due to its biological activity. It also finds applications in the semiconductor industry as a precursor for organic electronic materials. Additionally, it is explored in sensor technology for its unique chemical properties.

What precautions should be taken when handling Pyrazolo[1,5-a]pyridin-2(1H)-one (CAS: 59942-87-9)?

When handling Pyrazolo[1,5-a]pyridin-2(1H)-one, it is essential to wear protective clothing, including gloves and goggles. Work in a well-ventilated area or fume hood to minimize inhalation. Spills should be cleaned up using absorbent materials and proper disposal methods. Refer to the Safety Data Sheet (SDS) for detailed safety information.