[5-(Benzyloxy)-2-pyridinyl]methanol

Basic Information

View in Editor

CAS Number

59781-11-2

Molecular Formula

C13H13NO2

Molecular Weight

215.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

View in Editor

C1=CC=C(C=C1)COC2=CN=C(C=C2)CO

InChI

InChI=1S/C13H13NO2/c15-9-12-6-7-13(8-14-12)16-10-11-4-2-1-3-5-11/h1-8,15H,9-10H2

InChIKey

UTGLFQHWXNTFEV-UHFFFAOYSA-N

LogP

2.1529

Topological Polar Surface Area

42.35000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

192

Synonyms & References

English

5-benzyloxy-2-pyridinemethanol
SCHEMBL226721
(5-(Benzyloxy)pyridin-2-yl)methanol
MFCD16620236
AKOS017549669
(5-phenylmethoxypyridin-2-yl)methanol
DTXSID20471354
AB6301
UTGLFQHWXNTFEV-UHFFFAOYSA-N
CS-0210429
(5-benzyloxy-pyridin-2-yl)-methanol
59781-11-2
AS-44760
2-hydroxymethyl-5-benzyloxypyridine
2-Pyridinemethanol, 5-(phenylmethoxy)-

MDL Number

MFCD16620236

FAQ

What are the physical and chemical properties of [5-(Benzyloxy)-2-pyridinyl]methanol (CAS: 59781-11-2)?

[5-(Benzyloxy)-2-pyridinyl]methanol (CAS: 59781-11-2) is a white or off-white crystalline solid with a molecular weight of approximately 236.25 g/mol. It is sparingly soluble in water but soluble in common organic solvents like ethanol and acetone. This compound is moderately reactive, particularly in the presence of bases. It can undergo nucleophilic substitution reactions and form metal complexes.

How is [5-(Benzyloxy)-2-pyridinyl]methanol (CAS: 59781-11-2) typically synthesized?

Typically, [5-(Benzyloxy)-2-pyridinyl]methanol (CAS: 59781-11-2) is synthesized via reduction of 5-benzyloxy-2-pyridinecarbaldehyde using sodium borohydride in a solvent like methanol. The process involves the use of a pH buffer to maintain the appropriate reaction conditions, yielding a product with good selectivity and purity. The reaction is generally performed under mild conditions to ensure a high yield.

What industries use [5-(Benzyloxy)-2-pyridinyl]methanol (CAS: 59781-11-2)?

[5-(Benzyloxy)-2-pyridinyl]methanol (CAS: 59781-11-2) has applications in pharmaceuticals, where it serves as an intermediate for synthesizing various drugs. It is also used in polymers for its stabilizing properties and in sensors for its ability to bind to specific analytes. Additionally, it finds applications in semiconductors for its electronic properties.

What precautions should be taken when handling [5-(Benzyloxy)-2-pyridinyl]methanol (CAS: 59781-11-2)?

When handling [5-(Benzyloxy)-2-pyridinyl]methanol (CAS: 59781-11-2), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Ensure the work is conducted in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.