Glycopyrrolate

Basic Information

View in Editor

CAS Number

596-51-0

Molecular Formula

C19H28BrNO3

Molecular Weight

398.3 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

No data available

Melting Point

195°C

Boiling Point

No data available

Flash Point

No data available

Solubility

H2O: ≥24mg/mL

Refractive Index

1.6200 (estimate)

Vapor Pressure

No data available

SMILES

View in Editor

C[N+]1(CCC(C1)OC(=O)C(C2CCCC2)(C3=CC=CC=C3)O)C.[Br-]

InChI

InChI=1S/C19H28NO3.BrH/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15;/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3;1H/q+1;/p-1

InChIKey

VPNYRYCIDCJBOM-UHFFFAOYSA-M

LogP

-0.58090

Complexity

424

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

对湿度敏感、对热敏感

Toxicity

LD50 (72 hr.) in female mice, female rats (mg/kg): 107, 196 i.p.; in male rats (mg/kg): 1150 orally (Franko)

Synonyms & References

English

MLS002222301
Bromuro de glicopirronio
Tarodyl
Glycopyrronium (bromide);Glycopyrrolate (bromide)
EINECS 209-887-0
Glycopyrronii bromidum
3-Hydroxy-1,1-dimethylpyrrolidinium bromide alpha-cyclopentylmandelate
NC00280
FT-0626787
Pyrrolidinium, 3-hydroxy-1,1-dimethyl-, bromide, alpha-cyclopentylmandelate
NSC-251251
SCHEMBL41436
NCGC00179456-04
1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate
BCP07110
s4660
CHF-5259
HMS2097E14
A832400
MFCD00072137
Q27162963
Seebri Breezhaler
(1,1-dimethylpyrrolidin-1-ium-3-yl) 2-cyclopentyl-2-hydroxy-2-phenylacetate bromide
Glycopyrrolate, United States Pharmacopeia (USP) Reference Standard
G0392
NSC-250836
HMS2094A05
Pyrrolidinium, 3-[(cyclopentylhydroxyphenylacetyl)oxy]-1,1-dimethyl-,bromide
DTXCID103109
AD-237
Seebri breezhaler (TN)

MDL Number

MFCD00072137

Customs Code

2933990090

FAQ

What regulatory guidelines apply to Glycopyrrolate (CAS: 596-51-0)?

Glycopyrrolate (CAS: 596-51-0) must comply with the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) for hazardous substances. In the European Union, it falls under REACH regulations and may require a Substance Information Exchange Forum (SIEF) for compliance. In the USA, FDA and EPA regulations apply, particularly for its use in pharmaceuticals and environmental releases.

Are there alternatives to Glycopyrrolate (CAS: 596-51-0) in synthesis?

There are several alternatives to Glycopyrrolate (CAS: 596-51-0) in synthesis, including other quaternary ammonium compounds and glycopyrrolate analogs. Common reagents include 1-alkyl-3-[(2-hydroxyethoxy)methyl]-1-propanaminium chloride, which can serve as a suitable alternative depending on the specific requirements of the reaction.

What is the market or research trend for Glycopyrrolate (CAS: 596-51-0)?

The market for Glycopyrrolate (CAS: 596-51-0) is steadily growing, driven by its use as an anticholinergic agent in various medical applications. Research trends focus on its potential in treating conditions such as chronic obstructive pulmonary disease (COPD) and myasthenia gravis. Price trends indicate stability, with increasing demand in pharmaceutical applications.

How should waste containing Glycopyrrolate (CAS: 596-51-0) be handled?

Waste containing Glycopyrrolate (CAS: 596-51-0) should be collected in appropriate containers labeled with the hazardous material symbol. It should be incinerated or disposed of professionally to avoid environmental contamination. Proper disposal requires adherence to local regulations and should be managed by trained personnel to ensure safety and compliance with environmental protection laws.