(7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine dimaleate | CAS No. 59469-29-3

(7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine dimaleate

Basic Information

CAS Number

59469-29-3

Molecular Formula

C24H23ClFN3O8

Molecular Weight

535.91 g/mol

AD

Basic Physical Properties

Melting Point

196-198 ºC

C1C(NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F)CN.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O

InChI

InChI=1S/C16H15ClFN3.2C4H4O4/c17-10-5-6-15-13(7-10)16(20-9-11(8-19)21-15)12-3-1-2-4-14(12)18;2*5-3(6)1-2-4(7)8/h1-7,11,21H,8-9,19H2;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-

InChIKey

LYSTWDNEOGELCU-SPIKMXEPSA-N

LogP

2.4929000000000006

Topological Polar Surface Area

199.60999999999996 Ų

Hydrogen Bond Donor/Acceptor

7 / 11

Complexity

509

Synonyms & References

English

  • 59469-29-3
  • DTXSID601009883
  • 1H-1,4-Benzodiazepine-2-methanamine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-, (2Z)-2-butenedioate (1:2)
  • (Z)-but-2-enedioic acid;[7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methanamine
  • 2-Aminomethyl-7-chloro-2,3-dihydro-5-(2-fluorophenyl)-1H-1,4-benzodiazepine Dimaleate (1mg/ml in Acetonitrile)
  • 2-Aminomethyl-7-chloro-2,3-dihydro-5-(2-fluorophenyl)-1H-1,4-benzodiazepine Dimaleate
  • 2-AMINOMETHYL-7-CHLORO-2,3-DIHYDRO-5-(2-FLUOROPHENYL)-1H-1,4-BENZODIAZEPINE DIMALEATE

MDL Number

MFCD06795912

FAQ

What are the physical and chemical properties of (7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine dimaleate (CAS: 59469-29-3)?

7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine dimaleate has a crystalline form and a molecular weight of approximately 554.48 g/mol. Its solubility in water is low, and it is moderately soluble in organic solvents. It is known for its reactivity, particularly towards nucleophiles, and its stability under normal storage conditions.

How is (7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine dimaleate (CAS: 59469-29-3) typically synthesized?

(7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine dimaleate is synthesized through multi-step organic synthesis involving reactions such as diazepinization and maleation. Commonly used catalysts and reagents include sodium hydride and maleic anhydride. The synthesis typically achieves good yield and selectivity.

What industries use (7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine dimaleate (CAS: 59469-29-3)?

(7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine dimaleate is primarily used in the pharmaceutical industry for the development of various drugs. It has potential applications in semiconductors due to its electronic properties. Additionally, it may be used in sensors and other advanced materials due to its chemical functionality.

What precautions should be taken when handling (7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine dimaleate (CAS: 59469-29-3)?

When handling (7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine dimaleate, it is crucial to use personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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