Ethanesulfonyl chloride

Basic Information

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CAS Number

594-44-5

Molecular Formula

C2H5ClO2S

Molecular Weight

128.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Melting Point

-70°C

Boiling Point

177 °C

Refractive Index

n20/D 1.452(lit.)

SMILES

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CCS(=O)(=O)Cl

InChI

InChI=1S/C2H5ClO2S/c1-2-6(3,4)5/h2H2,1H3

InChIKey

FRYHCSODNHYDPU-UHFFFAOYSA-N

LogP

0.5749000000000001

Topological Polar Surface Area

34.14 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

108

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H310 Fatal in contact with skin
Acute toxicity, dermal

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H330 Fatal if inhaled
Acute toxicity, inhalation

Hazard Class

Class 6.1 Class 6.1

Sensitiveness

Moisture Sensitive

Synonyms & References

English

ethylsulfuryl chloride
ETHANESULFONYL CHLORIDE
F2190-0560
ETHANESULPHONYL CHLORIDE [HSDB]
ethanesulfonylchoride
InChI=1/C2H5ClO2S/c1-2-6(3,4)5/h2H2,1H
ethyl sulfonylchloride
EN300-20630
C2H5ClO2S
ethanesulfonic acid chloride
ethane sulfonyl chloride
EC 209-842-5
ETHANESULFONYL CHLORIDE, 594-44-5
NS00002525
UNII-B56ZOC898A
B56ZOC898A
SCHEMBL60402
STR04763
Q27274390
MFCD00007460
Ethylsulfochloride
ethyl-sulfonyl chloride
NSC8649
BRN 0773865
TL 77
FT-0625726
D78105
A832325
ethane-sulfonyl chloride
ethanesulphonylchloride
NSC 8649

MDL Number

MFCD00007460

Customs Code

2904909090

FAQ

What are the physical and chemical properties of Ethanesulfonyl chloride (CAS: 594-44-5)?

Ethanesulfonyl chloride is a colorless liquid with a molecular weight of approximately 148.06 g/mol. It has a pKa of 5, indicating weak acid behavior. The compound is highly soluble in water and organic solvents. It is a reactive compound, easily forming sulfoxides and sulfones under basic conditions. Its boiling point is around 122°C, and it is unstable to heat and basic conditions, making it prone to hydrolysis.

How is Ethanesulfonyl chloride (CAS: 594-44-5) typically synthesized?

Ethanesulfonyl chloride is typically synthesized by the reaction of ethanesulfonic acid with thionyl chloride. The reaction is conducted in a solvent such as dichloromethane at room temperature. The yield is generally high, and the reaction is selective, producing a pure product. Commonly, this process is carried out under anhydrous conditions to prevent side reactions.

What industries use Ethanesulfonyl chloride (CAS: 594-44-5)?

Ethanesulfonyl chloride finds applications in various industries. It is used in the pharmaceutical industry for the synthesis of certain drugs. In polymer chemistry, it serves as a functional monomer. Additionally, it is used in the production of sensors and semiconductor materials due to its reactive nature and ability to form stable derivatives.

What precautions should be taken when handling Ethanesulfonyl chloride (CAS: 594-44-5)?

When handling Ethanesulfonyl chloride, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place, away from heat and basic materials. Fume hoods should be used during handling to avoid inhalation. In case of a spill, neutralize the acid with a basic material and dispose of waste according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.