2-(2-Bromoethoxy)tetrahydro-2H-pyran

Basic Information

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CAS Number

59146-56-4

Molecular Formula

C7H13BrO2

Molecular Weight

209.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

62-64 °C0.4 mm Hg

Density

1.384 g/mL at 25 °C

Flash Point

190 °F

Refractive Index

n20/D 1.482(lit.)

SMILES

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C1CCOC(C1)OCCBr

InChI

InChI=1S/C7H13BrO2/c8-4-6-10-7-3-1-2-5-9-7/h7H,1-6H2

InChIKey

GCUOLJOTJRUDIZ-UHFFFAOYSA-N

LogP

1.9245

Topological Polar Surface Area

18.46 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

87.7

Synonyms & References

English

2H-Pyran, 2-(2-bromoethoxy)tetrahydro-, (A+/-)-
2-bromoethyl- tetrahydropyran-2-yl ether
2-(2'-bromoethoxy)tetrahydropyran
2-(2-bromo-ethoxy)-tetrahydropyran
2-Tetrahydropyran-2-yloxyethyl bromide
1-bromo-2-(tetrahydropyran-2-yloxy) ethane
AC-25469
2-(2-bromo-ethoxy)tetrahydropyran
2-(2-bromoethoxy)tetrahydro-2 h-pyran
2(2-bromoethoxy)tetrahydro-2h-pyran
1-bromo-2-tetrahydropyranyloxyethane
2-(2-tetrahydropyranyloxy)ethyl bromide
FT-0767882
2H-Pyran,2-(2-bromoethoxy)tetrahydro-
2-(tetrahydropyran-2-yl)oxyethyl bromide
2-(2-bromoethyl)oxytetrahydropyran
1-bromo-2-(tetrahydro-2-pyranyloxy)ethane
B2850
2-bromoethyltetrahydro-2-pyranylether
A3935
2-(2-bromoethyoxy)tetrahydropyran
2-(2-Bromoethoxyl)tetrahydropyran
2-(2-bromoethoxy)-tetra-hydropyran
2-bromo-1-tetrahydropyranyloxyethane
SY038937
A832181
NSC216078
2-(2-Bromoethoxy) tetrahydro-2H-pyran
1-bromo-2-(2- tetrahydropyranyloxy) ethane
2-(2-bromoethoxy)oxane
2-(2-bromoethoxy)tetrahydro-2H-piran

MDL Number

MFCD01321310

FAQ

What are the physical and chemical properties of 2-(2-Bromoethoxy)tetrahydro-2H-pyran (CAS: 59146-56-4)?

2-(2-Bromoethoxy)tetrahydro-2H-pyran is a colorless or white crystalline solid with a molecular weight of approximately 222.05 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and dichloromethane. This compound is reactive towards nucleophiles and can undergo nucleophilic substitution reactions. It is also susceptible to hydrolysis under basic conditions.

How is 2-(2-Bromoethoxy)tetrahydro-2H-pyran (CAS: 59146-56-4) typically synthesized?

2-(2-Bromoethoxy)tetrahydro-2H-pyran can be synthesized by the reaction of 1,2-epoxytetrahydro-2H-pyran with bromoethanol. This process typically involves the use of a base such as sodium hydride as a catalyst. The reaction selectively brominates the hydroxyl group, leading to a high yield of the desired product.

What industries use 2-(2-Bromoethoxy)tetrahydro-2H-pyran (CAS: 59146-56-4)?

2-(2-Bromoethoxy)tetrahydro-2H-pyran finds applications in the pharmaceutical industry as a building block for drug synthesis. It is also used in the production of polymers and sensors. Due to its reactive nature, it is also employed in semiconductor manufacturing processes where precise chemical functionalities are required.

What precautions should be taken when handling 2-(2-Bromoethoxy)tetrahydro-2H-pyran (CAS: 59146-56-4)?

When handling 2-(2-Bromoethoxy)tetrahydro-2H-pyran, it is essential to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation of vapors. Spills should be cleaned up carefully, and appropriate safety data sheets (SDS) should be consulted for specific handling instructions. Ensure adequate storage in a secure, cool, and dry location away from incompatible materials.