(1S)-1-(2-Pyridinyl)ethanol

Basic Information

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CAS Number

59042-90-9

Molecular Formula

C7H9NO

Molecular Weight

123.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

29°C

Boiling Point

95-98 ºC (12 Torr)

Density

1.082±0.06 g/cm3 (20 ºC 760 Torr),

Flash Point

81.2±20.4 ºC,

Refractive Index

n20/D 1.528

SMILES

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CC(C1=CC=CC=N1)O

InChI

InChI=1S/C7H9NO/c1-6(9)7-4-2-3-5-8-7/h2-6,9H,1H3/t6-/m0/s1

InChIKey

PPHIIIRFJKDTLG-LURJTMIESA-N

LogP

1.1349

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

Safety Information

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Hazard Statement

H227 Combustible liquid
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

H1263
(1S)-1-(pyridin-2-yl)ethan-1-ol
(S)-2-(1-Hydroxyethyl)pyridine
(1S)-1-pyridin-2-ylethanol
AS-59110
59042-90-9
(s)-1-(2-pyridyl)-ethanol
(S)- alpha -Methyl-2-pyridinemethanol
(S)-alpha-Methyl-2-pyridinemethanol, >=98.0% (GC)
(S)-alpha-Methyl-2-pyridinemethanol
C16040
A819235
MFCD06795465
(1S)-1-(2-pyridinyl)ethanol
SCHEMBL1193974
(S)-1-(Pyridin-2-yl)ethanol
(S)-2-(1-Hydroxyethyl) pyridine
(S)-1-Pyridin-2-yl-ethanol
(S)-1-(pyridin-2-yl)ethan-1-ol
EN300-54344
(S)-1-(2-Pyridyl)ethanol
PPHIIIRFJKDTLG-LURJTMIESA-N
(1S)-1-(2-pyridyl)ethanol
(S)-(-)-2-(1-HYDROXYETHYL)PYRIDINE
CS-0112596
AKOS016842971
2-[(S)-1-Hydroxyethyl]pyridine
(S)-1-(2-PYRIDYL)ETHANOL
(S)-2-(1-HYDROXYETHYL) PYRIDINE
(S)-ALPHA-METHYL-2-PYRIDINEMETHANOL
(s)-α-methyl-2-pyridinemethanol

MDL Number

MFCD06795465

Customs Code

2933399090

FAQ

What are the physical and chemical properties of (1S)-1-(2-Pyridinyl)ethanol (CAS: 59042-90-9)?

(1S)-1-(2-Pyridinyl)ethanol has a crystalline form and a molecular weight of approximately 144.18 g/mol. It is moderately soluble in water and ethanol. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It also displays some basic properties due to the pyridyl group.

How is (1S)-1-(2-Pyridinyl)ethanol (CAS: 59042-90-9) typically synthesized?

(1S)-1-(2-Pyridinyl)ethanol is typically synthesized via the reaction of 2-picolylamine with ethyl bromide in an alcohol solvent like ethanol, using a base such as potassium carbonate. The reaction yields a high purity product with good selectivity and a moderate to high yield, depending on the purity of starting materials and reaction conditions.

What industries use (1S)-1-(2-Pyridinyl)ethanol (CAS: 59042-90-9)?

(1S)-1-(2-Pyridinyl)ethanol is used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It also finds applications in the polymer industry for the modification of polymer surfaces and in the sensor industry for the development of gas sensors. Additionally, it is used in the semiconductor industry for the production of organic semiconductors.

What precautions should be taken when handling (1S)-1-(2-Pyridinyl)ethanol (CAS: 59042-90-9)?

When handling (1S)-1-(2-Pyridinyl)ethanol, use appropriate personal protective equipment (PPE), including gloves and safety goggles. Store the compound in a cool, dry place away from heat sources and incompatible materials. Use a fume hood during handling and disposal. Always refer to the Safety Data Sheet (SDS) for detailed information on handling, storage, and emergency procedures.