Nitrofurazone | CAS No. 59-87-0

Q: What is Nitrofurazone (CAS: 59-87-0)?

Nitrofurazone is an antimicrobial agent with the chemical formula C10H11N3O5S. It is a yellowish solid that is soluble in water and ethanol. This compound is known for its broad-spectrum antibacterial activity and is commonly used in topical applications for treating skin infections.

Q: What are the main uses of Nitrofurazone (CAS: 59-87-0)?

Nitrofurazone is primarily used in veterinary medicine and human healthcare as a topical antiseptic and antibiotic. It is found in wound dressings, ointments, and eye drops. Additionally, it is used in the pharmaceutical industry for manufacturing antibiotics and in research for studying antimicrobial properties.

Q: Is Nitrofurazone (CAS: 59-87-0) safe?

Nitrofurazone is generally considered safe when used as directed, but it may cause skin irritation or allergic reactions in some individuals. It is important to follow handling precautions, such as wearing gloves and avoiding contact with eyes. Safety standards recommend proper disposal to prevent environmental contamination.

Q: How should Nitrofurazone (CAS: 59-87-0) be stored?

Nitrofurazone should be stored in a cool, dry place away from direct light. It is best kept in a sealed, airtight container to maintain stability. Storage conditions should be between 15°C to 25°C (59°F to 77°F) and humidity levels below 60% to ensure product integrity and effectiveness.

Nitrofurazone

Basic Information

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CAS Number

59-87-0

Molecular Formula

C6H6N4O4

Molecular Weight

198.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

242-244 °C

Boiling Point

335.43°C (rough estimate)

Water Solubility

<0.1 g/100 mL at 19 ºC

Solubility

less than 1 mg/mL at 66° F (NTP, 1992)

Refractive Index

1.6500 (estimate)

Odor

ODORLESS

SMILES

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C1=C(OC(=C1)[N+](=O)[O-])C=NNC(=O)N

InChI

InChI=1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+

InChIKey

IAIWVQXQOWNYOU-FPYGCLRLSA-N

LogP

0.2

Complexity

261

Safety Information

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GHS Hazard Pictograms

H302

H317

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H317 May cause an allergic skin reaction
Sensitization, Skin

Hazard Class

Class 6.1(b) Class 6.1(b)

Sensitiveness

Light Sensitive

Toxicity

LD50 in rats (g/kg): 0.59 orally; 3.0 s.c. (Godwin)

Synonyms & References

English

NSC 1602
NCGC00090686-11
SMR000059012
Nitrofurazone, United States Pharmacopeia (USP) Reference Standard
Fracine
Nitrofurazone (Nitrofural)
(E)-2-((5-nitrofuran-2-yl)methylene)hydrazinecarboxamide
Monafuracis
(E)-2-((5-nitrofuran-2-yl)methylene)hydrazine-1-carboxamide
Vabrocid
HMS502G20
CAS-59-87-0
EN300-7476664
Fuvacillin
[(E)-(5-nitrofuran-2-yl)methylideneamino]urea
Furazina
NCGC00090686-01
Nitrofurazone (USP)
Monafuracin
MFCD00003225
1217220-85-3
IDI1_000778
NITROFURAZONE [GREEN BOOK]
NF-7
Furacine
NITROFURAZONE [INCI]
Cocafurin
Actin-N
Furaldon
NSC1602
Semikarbazon 5-nitrofurfuralu [Polish]

MDL Number

MFCD00003225

Customs Code

2934999090

FAQ

What is Nitrofurazone (CAS: 59-87-0)?

Nitrofurazone is an antimicrobial agent with the chemical formula C10H11N3O5S. It is a yellowish solid that is soluble in water and ethanol. This compound is known for its broad-spectrum antibacterial activity and is commonly used in topical applications for treating skin infections.

What are the main uses of Nitrofurazone (CAS: 59-87-0)?

Nitrofurazone is primarily used in veterinary medicine and human healthcare as a topical antiseptic and antibiotic. It is found in wound dressings, ointments, and eye drops. Additionally, it is used in the pharmaceutical industry for manufacturing antibiotics and in research for studying antimicrobial properties.

Is Nitrofurazone (CAS: 59-87-0) safe?

Nitrofurazone is generally considered safe when used as directed, but it may cause skin irritation or allergic reactions in some individuals. It is important to follow handling precautions, such as wearing gloves and avoiding contact with eyes. Safety standards recommend proper disposal to prevent environmental contamination.

How should Nitrofurazone (CAS: 59-87-0) be stored?

Nitrofurazone should be stored in a cool, dry place away from direct light. It is best kept in a sealed, airtight container to maintain stability. Storage conditions should be between 15°C to 25°C (59°F to 77°F) and humidity levels below 60% to ensure product integrity and effectiveness.