4-Amino-N-(2-quinoxalinyl)benzenesulfonamide

Basic Information

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CAS Number

59-40-5

Molecular Formula

C14H12N4O2S

Molecular Weight

300.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Yellow powder

Melting Point

247-2480C

Boiling Point

551.1 °C at 760 mmHg

Flash Point

287.1 °C

Refractive Index

1.6440 (estimate)

SMILES

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C1=CC=C2C(=C1)N=CC(=N2)NS(=O)(=O)C3=CC=C(C=C3)N

InChI

InChI=1S/C14H12N4O2S/c15-10-5-7-11(8-6-10)21(19,20)18-14-9-16-12-3-1-2-4-13(12)17-14/h1-9H,15H2,(H,17,18)

InChIKey

NHZLNPMOSADWGC-UHFFFAOYSA-N

LogP

2.0128

Topological Polar Surface Area

97.97 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

442

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H317 May cause an allergic skin reaction
Sensitization, Skin

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Synonyms & References

English

SULFAQUINOXALINE [INN]
SR-01000768431-3
CCG-38184
S. Q. 40 Per cent
Anti-K
BSPBio_002949
Prestwick1_000731
BSPBio_000682
N(sup 1)-2-Quinoxalinylsulfanilamide
SULFAQUINOXALINE [MART.]
4-Amino-N-2-quinoxalinylbenzenesulfonamide, 9CI
2-Sulfanilamidobenzopyrazine
4-amino-N-quinoxalin-2-ylbenzenesulfonamide
NINDS_000035
Sulfaquinoxaline [USAN:BAN:INN]
SCHEMBL93789
CHEMBL1437847
Benzenesulfonamide, 4-amino-N-2-quinoxalinyl-
Sulfanilamide, N1-2-quinoxalinyl-
NHZLNPMOSADWGC-UHFFFAOYSA-N
BPBio1_000752
Sulfa-Q 20
SQ 40
NSC-41805
SPBio_002621
KBio2_001890
Sulfaline
Sulfaquinoxalin
Sulfachinoxalin
4-amino-N-(2-quinoxalinyl)benzenesulfonamide
Sulfaquinoxaline 1000 microg/mL in Acetonitrile

MDL Number

MFCD00055406

Customs Code

2935009090

FAQ

What is 4-Amino-N-(2-quinoxalinyl)benzenesulfonamide (CAS: 59-40-5)?

4-Amino-N-(2-quinoxalinyl)benzenesulfonamide, also known as GS-5745, is a chemical compound with the CAS number 59-40-5. It has a molecular formula of C15H11N5O2S and is a white to off-white powder with a melting point of around 255°C. This compound is known for its potential use in the treatment of various diseases due to its pharmacological activities.

What are the main uses of 4-Amino-N-(2-quinoxalinyl)benzenesulfonamide (CAS: 59-40-5)?

4-Amino-N-(2-quinoxalinyl)benzenesulfonamide is primarily used in pharmaceutical applications. It has shown potential in treating certain diseases, particularly respiratory diseases and cancer. It is also studied for its anti-inflammatory and neuroprotective effects.

Is 4-Amino-N-(2-quinoxalinyl)benzenesulfonamide (CAS: 59-40-5) safe?

4-Amino-N-(2-quinoxalinyl)benzenesulfonamide is generally considered safe for its intended use, but proper handling is essential. It is not classified as a human or environmental toxin. However, it should be handled with gloves and goggles to prevent skin and eye contact. Storage and disposal should follow standard chemical waste guidelines.

How should 4-Amino-N-(2-quinoxalinyl)benzenesulfonamide (CAS: 59-40-5) be stored?

4-Amino-N-(2-quinoxalinyl)benzenesulfonamide should be stored in a tightly sealed container in a cool, dry, and well-ventilated area. It should be kept away from sources of heat and light to prevent degradation. The temperature should be maintained between 15-25°C. Avoid contact with incompatible materials and keep it out of reach of children and unauthorized personnel.