2-Quinolinol

Basic Information

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CAS Number

59-31-4

Molecular Formula

C9H7NO

Molecular Weight

145.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

194.0 to 201.0 deg-C

Boiling Point

346.7°C at 760 mmHg

Flash Point

200.6℃

Solubility

alcohol: soluble(lit.)

Refractive Index

1.4500 (estimate)

SMILES

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C1=CC=C2C(=C1)C=CC(=O)N2

InChI

InChI=1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11)

InChIKey

LISFMEBWQUVKPJ-UHFFFAOYSA-N

LogP

1.5280999999999998

pKa

-0.31, 11.76(at 20℃)

Topological Polar Surface Area

32.86 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

198

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

BDBM50366034
PS-4021
W-104563
1H-quinolinone
quinolin-2-one
AKOS003297745
2-Hydroxyquinoline, 98%
MFCD00006743
alpha-Quinolone
2-Quinolinone
quino- lone
C06338
NSC554
Carbostyril (VAN)
NSC 156783
803BHY7QWU
CARBOSTYRIL [MI]
FT-0612637
UNII-803BHY7QWU
1H-quinolone
2-Quinolone
Oc1ccc2ccccc2n1
SY003693
2-[1h]-quinolone
EINECS 200-420-6
BP-10114
hydroquinolin-2-one
AMY23222
.alpha.-Quinolone
F0001-1542
SB37816

MDL Number

MFCD00006743

Customs Code

2933499090

FAQ

What are the physical and chemical properties of 2-Quinolinol (CAS: 59-31-4)?

2-Quinolinol (CAS: 59-31-4) is a crystalline solid with a molecular weight of approximately 135.15 g/mol. It is slightly soluble in water and ethanol but more soluble in organic solvents like methanol and acetone. Chemically, it exhibits basic properties and is a weak base. It is stable under normal conditions but reacts with strong acids to form quinoline salts.

How is 2-Quinolinol (CAS: 59-31-4) typically synthesized?

2-Quinolinol is typically synthesized by reduction of 2-quinolinecarboxaldehyde with sodium borohydride. Other methods include the reaction of 2-aminobenzaldehyde with quinoline or the reduction of 2-quinolinecarboxylic acid with lithium aluminum hydride. These methods yield high selectivity and good to excellent yields.

What industries use 2-Quinolinol (CAS: 59-31-4)?

2-Quinolinol is used in the pharmaceutical industry for the synthesis of drugs, in the polymer industry for the production of functional polymers, in the sensor industry for gas sensors, and in the semiconductor industry for photoresists and lithography. It is also used as a chelating agent and in the development of dyes and pigments.

What precautions should be taken when handling 2-Quinolinol (CAS: 59-31-4)?

When handling 2-Quinolinol (CAS: 59-31-4), it is important to use appropriate personal protective equipment (PPE), such as gloves and safety goggles. Store the compound in a cool, well-ventilated area away from incompatible materials. Use fume hoods during handling to avoid inhalation. For spills, immediately clean up using appropriate absorbents and dispose of the waste according to local regulations. Always refer to the SDS for detailed safety information.