Amikacin EP Impurity D

Basic Information

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CAS Number

59-01-8

Molecular Formula

C18H36N4O11

Molecular Weight

484.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

581.13°C (rough estimate)

Refractive Index

1.6700 (estimate)

Specific Rotation

D24 +146° (0.1N H2SO4)

SMILES

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C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N

InChI

InChI=1S/C18H36N4O11/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17/h4-18,23-29H,1-3,19-22H2/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-/m1/s1

InChIKey

SBUJHOSQTJFQJX-NOAMYHISSA-N

LogP

-7.2913999999999985

Topological Polar Surface Area

282.61 Å²

Hydrogen Bond Donor/Acceptor

15 / 15

Complexity

638

Safety Information

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Toxicity

LD50 i.v. in mice: 583 mg/kg (Wakazawa)

Synonyms & References

English

8063-07-8
Kanamycin Complex
Kanamicina [Italian]
Kanamycin sulfate, Antibiotic for Culture Media Use Only
KM (the Antibiotic)
IDI1_000024
Kanamycine [INN-French]
AS-14003
Kanamycin A Deuterated
CS-0006792
CHEBI:6104
D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1,4))-2-deoxy-
KanamycinA
K-0250
(1S,2R,3R,4S,6R)-4,6-diamino-3-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside
KAN
59-01-8
4,6-Diamino-2-hydroxy-1,3-cyclohexane 3,6'diamino-3,6'-dideoxydi-alpha-D-glucoside
D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1-4))-2-deoxy-
SCHEMBL2735
HSDB 3107
Kanamycin,(S)
4,6-diamino-2-hydroxy-1,3-cyclohexylene 3,6'-diamino-3,6'-dideoxydi-D-glucopyranoside
Prestwick3_000394
AB00513827
BPBio1_000669
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-((1R,2R,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-2-hydroxycyclohexyloxy)tetrahydro-2H-pyran-3,4,5-triol
NS00098990
SBUJHOSQTJFQJX-NOAMYHISSA-N
BRD-K08327065-065-01-9
DB01172

MDL Number

MFCD00070289

FAQ

What regulatory guidelines apply to Amikacin EP Impurity D (CAS: 59-01-8)?

Amikacin EP Impurity D (CAS: 59-01-8) must comply with regulatory guidelines such as GHS classification for hazardous materials, REACH regulations in the EU, and FDA/EPA requirements for pharmaceuticals and environmental safety. It is essential to adhere to these guidelines for safe handling and disposal.

Are there alternatives to Amikacin EP Impurity D (CAS: 59-01-8) in synthesis?

Alternatives to Amikacin EP Impurity D (CAS: 59-01-8) in synthesis include other aminoglycosides like gentamicin and tobramycin, which can serve similar functions in certain applications. However, the choice of alternative depends on specific requirements and regulatory compliance.

What is the market or research trend for Amikacin EP Impurity D (CAS: 59-01-8)?

The market for Amikacin EP Impurity D (CAS: 59-01-8) is trending towards increasing demand in pharmaceutical research due to its use in studying antibiotic resistance and efficacy. Research trends focus on understanding its interactions and potential applications in new drug development.

How should waste containing Amikacin EP Impurity D (CAS: 59-01-8) be handled?

Waste containing Amikacin EP Impurity D (CAS: 59-01-8) should be handled in accordance with environmental protection guidelines. Collection should be done in sealed containers, followed by incineration or professional waste disposal to ensure safe and compliant disposal, adhering to local and international regulations.