(2S,3S)-2,3-Dihydroxysuccinic acid - 17-(cyclobutylmethyl)morphinan-3,14-diol (1:1) | CAS No. 58786-99-5

(2S,3S)-2,3-Dihydroxysuccinic acid - 17-(cyclobutylmethyl)morphinan-3,14-diol (1:1)

Basic Information

CAS Number

58786-99-5

Molecular Formula

C25H35NO8

Molecular Weight

477.55 g/mol

AD

Basic Physical Properties

Melting Point

217-219°

Specific Rotation

D22 -64.0° (c = 0.4 in methanol)

C1CCC2(C3CC4=C(C2(C1)CCN3CC5CCC5)C=C(C=C4)O)O.C(C(C(=O)O)O)(C(=O)O)O

InChI

InChI=1S/C21H29NO2.C4H6O6/c23-17-7-6-16-12-19-21(24)9-2-1-8-20(21,18(16)13-17)10-11-22(19)14-15-4-3-5-15;5-1(3(7)8)2(6)4(9)10/h6-7,13,15,19,23-24H,1-5,8-12,14H2;1-2,5-6H,(H,7,8)(H,9,10)/t19-,20+,21-;1-,2-/m10/s1

InChIKey

GMTYREVWZXJPLF-AFHUBHILSA-N

LogP

1.2429999999999997

Topological Polar Surface Area

158.76 Ų

Hydrogen Bond Donor/Acceptor

6 / 9

Complexity

626

Safety Information

View Safety Information

Hazard Class

Class 6.1(a) Class 6.1(a)

Toxicity

LD50 in mice, rats (mg/kg): 40-57, 17-20 i.v.; 395-527, 570-756 orally (Heel)

Synonyms & References

English

  • BUTORPHANOL TARTRATE [JAN]
  • Butorphanol Tartrate Preservative Free
  • EINECS 261-443-5
  • 17-(Cyclobutylmethyl)morphinan-3,14-diyl (S-(R*,R*))-2,3-dihydroxysuccinate
  • BUTORPHANOL TARTRATE (USP MONOGRAPH)
  • Q27068142
  • Morphinan-3,14-diol, 17-(cyclobutylmethyl)-, [S-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt)
  • DTXCID001333701
  • BUTORPHANOL TARTRATE [WHO-DD]
  • BUTORPHANOL TARTRATE [GREEN BOOK]
  • DTXSID50904569
  • Butorphanol tartrate (USAN:USP:BAN:JAN)
  • Morphinan-3,14-diol, 17-(cyclobutylmethyl)-, (2S,3S)-2,3-dihydroxybutanedioate (1:1)
  • 17-(cyclobutylmethyl)morphinan-3,14-diol (2S,3S)-2,3-dihydroxybutanedioate
  • Butorphic
  • Dolorex
  • TorbugesicSA
  • DEA No. 9720
  • Torate
  • 2L7I72RUHN
  • Butorphanol Tartrate Injection
  • (-)-N-cyclobutylmethyl-3,14-dihydroxymorphinan D-(-)-tartrate
  • BUTORPHANOL TARTRATE [ORANGE BOOK]
  • (-)-17-(Cyclobutylmethyl)morphinan-3,14-diol D-(-)-tartrate (1:1) (salt)
  • Torbutrol Injection
  • Stadol NS
  • CHEBI:3243
  • (-)-17-(cyclobutylmethyl)morphinan-3,14-diol D-(-)-tartrate
  • Butorphanol (tartrate)
  • Torbutrol Tablets
  • butorphanol D-tartrate

FAQ

What regulatory guidelines apply to (2S,3S)-2,3-Dihydroxysuccinic acid - 17-(cyclobutylmethyl)morphinan-3,14-diol (CAS: 58786-99-5)?

The compound (2S,3S)-2,3-Dihydroxysuccinic acid - 17-(cyclobutylmethyl)morphinan-3,14-diol (CAS: 58786-99-5) is subject to various regulatory guidelines, including the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations, and FDA/EPA requirements. It is important to follow specific labeling, storage, and disposal guidelines to ensure safety and compliance.

Are there alternatives to (2S,3S)-2,3-Dihydroxysuccinic acid - 17-(cyclobutylmethyl)morphinan-3,14-diol (CAS: 58786-99-5) in synthesis?

Alternatives to (2S,3S)-2,3-Dihydroxysuccinic acid - 17-(cyclobutylmethyl)morphinan-3,14-diol (CAS: 58786-99-5) include similar compounds such as isomers or analogs. Common alternatives in synthesis include using different starting materials or reagents, such as 2,3-dihydroxybutanedioic acid, which can serve as a precursor in the synthesis of similar compounds.

What is the market or research trend for (2S,3S)-2,3-Dihydroxysuccinic acid - 17-(cyclobutylmethyl)morphinan-3,14-diol (CAS: 58786-99-5)?

The market for (2S,3S)-2,3-Dihydroxysuccinic acid - 17-(cyclobutylmethyl)morphinan-3,14-diol (CAS: 58786-99-5) is growing due to its potential applications in pharmaceuticals. Research trends include exploring its use in pain management and other therapeutic areas. Market trends show increasing demand for novel compounds with specific pharmacological properties.

How should waste containing (2S,3S)-2,3-Dihydroxysuccinic acid - 17-(cyclobutylmethyl)morphinan-3,14-diol (CAS: 58786-99-5) be handled?

Waste containing (2S,3S)-2,3-Dihydroxysuccinic acid - 17-(cyclobutylmethyl)morphinan-3,14-diol (CAS: 58786-99-5) should be collected in a suitable container and stored away from direct sunlight and heat. It should be disposed of through professional waste management services, following local and international regulations for hazardous waste. Environmental protection precautions, such as minimizing exposure to air and water, are crucial during handling and disposal.

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