cyclopropyl(4-methoxyphenyl)methanamine hydrochloride

Basic Information

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CAS Number

58271-59-3

Molecular Formula

C11H16ClNO

Molecular Weight

213.71 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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Cl.COc1ccc(cc1)C(N)C2CC2

InChI

InChI=1S/C11H15NO.ClH/c1-13-10-6-4-9(5-7-10)11(12)8-2-3-8;/h4-8,11H,2-3,12H2,1H3;1H

InChIKey

WNXIXBPARKOHLB-UHFFFAOYSA-N

LogP

2.5268000000000006

Topological Polar Surface Area

35.25 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

160

Synonyms & References

English

Cyclopropyl(4-methoxyphenyl)methanamine hydrochloride
CYCLOPROPYL(4-METHOXYPHENYL)METHYLAMINE HCl
CYCLOPROPYL(4-METHOXYPHENYL)METHYLAMINE-HCL
N-[(4-methoxyphenyl)methyl]cyclopropanamine,hydrochloride
Cyclopropyl(4-methoxyphenyl)methanamine HCl
AK134059
AM100990
ST2406764
W7143
CYCLOPROPYL(4-METHOXYPHENYL)METHANAMINE, HCL
cyclopropyl-(4-methoxyphenyl)methanamine;hydrochloride
(R)-cyclopropyl-(4-methoxyphenyl)methanamine;hydrochloride
(S)-cyclopropyl-(4-methoxyphenyl)methanamine;hydrochloride

MDL Number

MFCD00198042

Customs Code

2922299090

FAQ

What are the physical and chemical properties of cyclopropyl(4-methoxyphenyl)methanamine hydrochloride (CAS: 58271-59-3)?

Cyclopropyl(4-methoxyphenyl)methanamine hydrochloride is a white crystalline solid. Its molecular weight is approximately 233.36 g/mol. The compound is soluble in organic solvents such as ethanol and methanol. It has a pKa of about 10.1 and moderate basicity. Chemically, it reacts with acids to form the free base and exhibits good reactivity with electrophiles.

How is cyclopropyl(4-methoxyphenyl)methanamine hydrochloride (CAS: 58271-59-3) typically synthesized?

Cyclopropyl(4-methoxyphenyl)methanamine hydrochloride can be synthesized through a multi-step process. Initially, cyclopropylamine is reacted with 4-methoxybenzyl chloride to form the corresponding amine chloride. This intermediate is then treated with sodium hydroxide to obtain the free base, which is subsequently converted to the hydrochloride salt by treatment with hydrochloric acid. This process ensures high yield and good selectivity.

What industries use cyclopropyl(4-methoxyphenyl)methanamine hydrochloride (CAS: 58271-59-3)?

Cyclopropyl(4-methoxyphenyl)methanamine hydrochloride is primarily used in the pharmaceutical industry for the development of certain drugs. It may also have applications in polymer chemistry and as a precursor in the synthesis of functional materials, including sensors and semiconductors.

What precautions should be taken when handling cyclopropyl(4-methoxyphenyl)methanamine hydrochloride (CAS: 58271-59-3)?

When handling cyclopropyl(4-methoxyphenyl)methanamine hydrochloride, ensure the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Store it in a cool, dry place away from direct sunlight and heat sources. In case of spill, sweep up the solid and dispose of it according to the safety data sheet (SDS). Always refer to the latest SDS for specific instructions.