Compound Q&A

How is cyclopropyl(4-methoxyphenyl)methanamine hydrochloride (CAS: 58271-59-3) typically synthesized?

Answer

cyclopropyl(4-methoxyphenyl)methanamine hydrochloride
Cyclopropyl(4-methoxyphenyl)methanamine hydrochloride can be synthesized through a multi-step process. Initially, cyclopropylamine is reacted with 4-methoxybenzyl chloride to form the corresponding amine chloride. This intermediate is then treated with sodium hydroxide to obtain the free base, which is subsequently converted to the hydrochloride salt by treatment with hydrochloric acid. This process ensures high yield and good selectivity.

About

CAS No 58271-59-3
English Name cyclopropyl(4-methoxyphenyl)methanamine hydrochloride
Molecular Formula C11H16ClNO
Molecular Weight 213.71 g/mol
SMILES Cl.COc1ccc(cc1)C(N)C2CC2
InChIKey WNXIXBPARKOHLB-UHFFFAOYSA-N
Last Updated: 2025-11-28 19:29

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