1,2,3,4-Tetrahydro-7-quinolinol

Basic Information

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CAS Number

58196-33-1

Molecular Formula

C9H11NO

Molecular Weight

149.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Light-red to Brown Solid

Boiling Point

319.7°C at 760 mmHg

Density

1.141 g/cm3

Flash Point

174.7 °C

Refractive Index

1.582

SMILES

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C1CC2=C(C=C(C=C2)O)NC1

InChI

InChI=1S/C9H11NO/c11-8-4-3-7-2-1-5-10-9(7)6-8/h3-4,6,10-11H,1-2,5H2

InChIKey

HJJRGZMJZDSMDB-UHFFFAOYSA-N

LogP

1.7503

Topological Polar Surface Area

32.26 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

138

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

DS-10738
AKOS005259159
A8252
Z1198176201
AMY5106
CS-W003468
7-Hydroxy-1 pound not2 pound not3 pound not4-tetrahydroquinoline
EN300-119749
1,2,3,4-Tetrahydro-7-quinolinol
FT-0645214
7-Quinolinol, 1,2,3,4-tetrahydro-
DTXSID7069235
BCP13852
1,2,3,4-Tetrahydro-quinolin-7-ol
MFCD08063887
HJJRGZMJZDSMDB-UHFFFAOYSA-N
1,2,3,4-tetrahydro-7-hydroxyquinoline
58196-33-1
1,2,3,4-tetrahydroquinolin-7-ol
7-Hydroxy-1,2,3,4-tetrahydroquinoline
7-Hydroxy-1,2,3,4-Tetrahydro Quinoline
7-hydroxy-1,2,3,4-Tetrahydro-quinolin
7-Hydroxy-1,2,3,4-tetrahydroquinoline, AldrichCPR
AC-518
SY021160
SCHEMBL1119368
1,2,3,4-Tetrahydro-7-hydroxychinolin
1,2,3,4-tetrahydrochinolin-7-ol
1,2,3,4-tetrahydro-quinolin-7-ol
7-hydroxyl-1,2,3,4-tetrahydroquinoline
7-Quinolinol,1,2,3,4-tetrahydro

MDL Number

MFCD08063887

Customs Code

2933499090

FAQ

What are the physical and chemical properties of 1,2,3,4-Tetrahydro-7-quinolinol (CAS: 58196-33-1)?

1,2,3,4-Tetrahydro-7-quinolinol is a white crystalline solid with a molecular weight of approximately 166.16 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. It is less reactive than its parent compound, 7-quinolinol, and shows stability under normal laboratory conditions. It is a basic compound and can form salts with acidic compounds.

How is 1,2,3,4-Tetrahydro-7-quinolinol (CAS: 58196-33-1) typically synthesized?

1,2,3,4-Tetrahydro-7-quinolinol can be synthesized by reducing 7-quinolinone in the presence of a reducing agent like sodium borohydride. The reaction typically requires a solvent such as ethanol or tetrahydrofuran (THF) and proceeds with good selectivity and yield. The reduction process is performed under an inert atmosphere to prevent side reactions.

What industries use 1,2,3,4-Tetrahydro-7-quinolinol (CAS: 58196-33-1)?

1,2,3,4-Tetrahydro-7-quinolinol is primarily used in the pharmaceutical industry for the development of certain types of drugs. It is also used in the semiconductor industry as a chemical intermediate and in the synthesis of various functional materials used in electronic devices. Additionally, it is used in the polymer industry to modify the properties of polymers for specific applications.

What precautions should be taken when handling 1,2,3,4-Tetrahydro-7-quinolinol (CAS: 58196-33-1)?

When handling 1,2,3,4-Tetrahydro-7-quinolinol, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. The compound should be handled in a fume hood to minimize exposure to vapors. In case of a spill, ensure that the area is well-ventilated and dispose of the spill according to the manufacturer's guidelines or local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.