6-Quinolinamine dihydrochloride

Basic Information

View in Editor

CAS Number

580-15-4

Molecular Formula

C9H10Cl2N2

Molecular Weight

144.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Powder

Melting Point

114.0 to 118.0 deg-C

Boiling Point

187°C/11mmHg

Water Solubility

Soluble in methanol, chloroform, ethanol, and benzene. Insoluble in water.

Flash Point

146°C/0.3mm

Refractive Index

1.7080 (estimate)

SMILES

View in Editor

C1=CC2=C(C=CC(=C2)N)N=C1

InChI

InChI=1S/C9H8N2.2ClH/c10-8-3-4-9-7(6-8)2-1-5-11-9;;/h1-6H,10H2;2*1H

InChIKey

DYLXUOKGBWKRLK-UHFFFAOYSA-N

LogP

1.817

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

136

Safety Information

View Safety Information

GHS Hazard Pictograms

H315

H319

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Class AIR SENSITIVE Class AIR SENSITIVE

Sensitiveness

Air Sensitive

Synonyms & References

English

Quinoline, 6-amino-
HY-W007404
6-amino quinoline
MFCD00006803
PS-4529
W-105419
6-AMINOQUINOLINE
BDBM32026
FT-0620944
A18930
NSC58388
quinolin-6-yl amine
Q27460051
ES5
F2190-0533
BB 0221206
SCHEMBL160217
6-Quinolinamine
6-quinolylamine
Z255114686
MLS000080747
CHEMBL99408
AC-4708
NSC-58388
HMS2451C16
A1370
BIDD:GT0636
NSC 58388
SMR000036663
3kqp
EINECS 209-453-0

MDL Number

MFCD00006803

Customs Code

2933499090

FAQ

What are the physical and chemical properties of 6-Quinolinamine dihydrochloride (CAS: 580-15-4)?

6-Quinolinamine dihydrochloride is a white crystalline solid with a molecular weight of approximately 262.65 g/mol. It is soluble in water and less soluble in organic solvents like ethanol and dichloromethane. Chemically, it is mildly basic and can react with acids to form the dihydrochloride salt. It is stable under normal conditions but should be stored away from moisture and heat to prevent degradation.

How is 6-Quinolinamine dihydrochloride (CAS: 580-15-4) typically synthesized?

6-Quinolinamine dihydrochloride can be synthesized by reacting 6-aminouracil with hydrochloric acid. The process involves heating a solution of 6-aminouracil in a suitable solvent with an excess of hydrochloric acid. The yield is typically around 85-90%, and the product is isolated by recrystallization from water. The reaction is selective and proceeds smoothly under mild conditions.

What industries use 6-Quinolinamine dihydrochloride (CAS: 580-15-4)?

6-Quinolinamine dihydrochloride has applications in various industries. It is used as a precursor in the synthesis of pharmaceuticals, particularly in the development of antiviral and anti-inflammatory drugs. It also finds use in the production of certain sensors and semiconductors, as well as in polymer synthesis for its stabilizing properties.

What precautions should be taken when handling 6-Quinolinamine dihydrochloride (CAS: 580-15-4)?

When handling 6-Quinolinamine dihydrochloride (CAS: 580-15-4), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be flushed with water. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.