2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine | CAS No. 58-38-8

2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine

Basic Information

CAS Number

58-38-8

Molecular Formula

C20H24ClN3S

Molecular Weight

373.9 g/mol

AD

Basic Physical Properties

Melting Point

228 ºC

Boiling Point

524.8°Cat760mmHg

Flash Point

271.2°C

Refractive Index

1.6000 (estimate)

CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl

InChI

InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3

InChIKey

WIKYUJGCLQQFNW-UHFFFAOYSA-N

LogP

log Kow = 4.88

Topological Polar Surface Area

9.72 Ų

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

429

Synonyms & References

English

  • BRD-K19352500-070-02-5
  • LS-105399
  • KBio2_007440
  • PROCHLORPERAZINE [MI]
  • 6140 RP
  • PROCHLORPERAZINE [JAN]
  • 2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid
  • MLS001148133
  • Nipodal
  • 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine
  • Probes1_000265
  • Compazine
  • Prestwick1_000399
  • 2-chloro-10-(3-(4-methylpiperazin-1-yl)propyl)-10h-phenothiazine
  • CHLOPERAZINE
  • Compazine (*Maleate*)
  • SPBio_001333
  • Prochlorpemazine
  • Prochlorperazine [USAN:INN:BAN:JAN]
  • Emelent
  • N-(.gamma.-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazine
  • Phenotil (TN)
  • Eskatrol
  • BSPBio_000617
  • N-(gamma-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazine
  • SBI-0051005.P004
  • CAS-84-02-6
  • CHEMBL728
  • RP-6140
  • Prochlorperazine mesylate
  • MRF-0000068

MDL Number

MFCD00056797

Customs Code

29159020

FAQ

What regulatory guidelines apply to 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (CAS: 58-38-8)?

2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (CAS: 58-38-8) is classified under the Globally Harmonized System (GHS) as a hazardous chemical due to its potential health impacts. In the European Union, it is regulated under the REACH regulations for the registration, evaluation, authorization, and restriction of chemicals. Additionally, the FDA and EPA may have specific requirements for its use and disposal in the United States.

Are there alternatives to 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (CAS: 58-38-8) in synthesis?

Yes, there are alternatives to 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (CAS: 58-38-8) in synthesis. Common alternatives include 2-(4-Methylpiperazin-1-yl)ethyl)-10H-phenothiazine and various 10H-phenothiazine derivatives. These alternatives can offer similar functionalities but with potentially different synthetic pathways or reagents.

What is the market or research trend for 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (CAS: 58-38-8)?

The market trend for 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (CAS: 58-38-8) is driven by its applications in pharmaceuticals and research. Recent research trends focus on its potential as an antipsychotic and antidepressant agent. However, due to its toxicity, there is also increasing interest in developing more potent and selective derivatives with reduced side effects.

How should waste containing 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (CAS: 58-38-8) be handled?

Waste containing 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (CAS: 58-38-8) should be handled under strict environmental protection precautions. It is recommended to collect waste liquids in appropriate containers and seal them properly. For larger quantities, professional waste disposal services should be utilized. Incineration may be an option, but it must comply with local regulations to ensure safe and effective disposal.

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